Metabolomic Analysis of Bone Morphogenetic Protein Receptor Type 2 Mutations in Human Pulmonary Endothelium Reveals Widespread Metabolic Reprogramming

Metabolic Reprogramming ◽

Receptor Type ◽

Metabolomic Analysis ◽

Pulmonary Endothelium ◽

Protein Receptor ◽

N-linked glycosylation of the bone morphogenetic protein receptor type 2 (BMPR2) enhances ligand binding

Cellular and Molecular Life Sciences ◽

10.1007/s00018-013-1541-8 ◽

2013 ◽

Vol 71 (16) ◽

pp. 3165-3172 ◽

Cited By ~ 9

Author(s):

Jonathan W. Lowery ◽

Jose M. Amich ◽

Alex Andonian ◽

Vicki Rosen

Keyword(s):

Ligand Binding ◽

Receptor Type ◽

Protein Receptor ◽

Bone Morphogenetic Protein Receptor Type 2 Mutation in Pulmonary Arterial Hypertension

Circulation ◽

10.1161/circulationaha.115.020696 ◽

2016 ◽

Vol 133 (18) ◽

pp. 1747-1760 ◽

Cited By ~ 38

Author(s):

Cathelijne E. van der Bruggen ◽

Chris M. Happé ◽

Peter Dorfmüller ◽

Pia Trip ◽

Onno A. Spruijt ◽

...

Keyword(s):

Arterial Hypertension ◽

Receptor Type ◽

Protein Receptor ◽

Morphogenetic Protein ◽

Faculty Opinions recommendation of Characteristics of pulmonary arterial hypertension in affected carriers of a mutation located in the cytoplasmic tail of bone morphogenetic protein receptor type 2.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725248959.793502022 ◽

2014 ◽

Author(s):

Vinicio de Jesus Perez

Keyword(s):

Arterial Hypertension ◽

Cytoplasmic Tail ◽

Receptor Type ◽

Protein Receptor ◽

Morphogenetic Protein ◽

Subcellular Mechanisms in Pulmonary Arterial Hypertension: Combinatorial Modalities that Inhibit Anterograde Trafficking and Cause Bone Morphogenetic Protein Receptor Type 2 Mislocalization

Pulmonary Circulation ◽

10.1086/674336 ◽

2013 ◽

Vol 3 (3) ◽

pp. 533-550 ◽

Cited By ~ 6

Author(s):

Yang-Ming Yang ◽

Kirk B. Lane ◽

Pravin B. Sehgal

Keyword(s):

Arterial Hypertension ◽

Receptor Type ◽

Protein Receptor ◽

Morphogenetic Protein ◽

Characteristics of Pulmonary Arterial Hypertension in Affected Carriers of a Mutation Located in the Cytoplasmic Tail of Bone Morphogenetic Protein Receptor Type 2

CHEST Journal ◽

10.1378/chest.14-0880 ◽

2015 ◽

Vol 147 (5) ◽

pp. 1385-1394 ◽

Cited By ~ 23

Author(s):

Barbara Girerd ◽

Florence Coulet ◽

Xavier Jaïs ◽

Mélanie Eyries ◽

Cathelijne Van Der Bruggen ◽

...

Keyword(s):

Arterial Hypertension ◽

Cytoplasmic Tail ◽

Receptor Type ◽

Protein Receptor ◽

Morphogenetic Protein ◽

Dysregulated zinc and sphingosine‐1‐phosphate signalling in pulmonary hypertension: potential effects by targeting of bone morphogenetic protein receptor type 2 in pulmonary microvessels

Cell Biology International ◽

10.1002/cbin.11682 ◽

2021 ◽

Author(s):

Hai B Tran ◽

Suzanne Maiolo ◽

Rebecca Harper ◽

Peter D Zalewski ◽

Paul Reynolds ◽

...

Keyword(s):

Pulmonary Hypertension ◽

Receptor Type ◽

Protein Receptor ◽

Morphogenetic Protein ◽

Sphingosine 1 Phosphate ◽

Pulmonary Microvessels

Mechanisms of Lipid Accumulation in the Bone Morphogenetic Protein Receptor Type 2 Mutant Right Ventricle

American Journal of Respiratory and Critical Care Medicine ◽

10.1164/rccm.201507-1444oc ◽

2016 ◽

Vol 194 (6) ◽

pp. 719-728 ◽

Cited By ~ 41

Author(s):

Megha H. Talati ◽

Evan L. Brittain ◽

Joshua P. Fessel ◽

Niki Penner ◽

James Atkinson ◽

...

Keyword(s):

Right Ventricle ◽

Lipid Accumulation ◽

Receptor Type ◽

Protein Receptor ◽

Interaction between Bone Morphogenetic Protein Receptor Type 2 and Estrogenic Compounds in Pulmonary Arterial Hypertension

Pulmonary Circulation ◽

10.1086/674312 ◽

2013 ◽

Vol 3 (3) ◽

pp. 564-577 ◽

Cited By ~ 32

Author(s):

Joshua P. Fessel ◽

Xinping Chen ◽

Andrea Frump ◽

Santhi Gladson ◽

Tom Blackwell ◽

...

Keyword(s):

Arterial Hypertension ◽

Receptor Type ◽

Estrogenic Compounds ◽

Protein Receptor ◽

Morphogenetic Protein ◽

Changes In Smad Signaling Leads To Amelioration Of Pulmonary Arterial Hypertension Following Gene Delivery Of Bone Morphogenetic Protein Receptor Type 2

10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a6517 ◽

2012 ◽

Author(s):

Rebecca L. Timo ◽

Ann M. Reynolds ◽

Paul N. Reynolds

Keyword(s):

Gene Delivery ◽

Arterial Hypertension ◽

Receptor Type ◽

Protein Receptor ◽

Morphogenetic Protein ◽

Gene Delivery of Bone Morphogenetic Protein Receptor Type-2 Attenuates Established Hypoxic and Monocrotaline-Induced Pulmonary Hypertension

10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a6333 ◽

2010 ◽

Author(s):

Ann M. Reynolds ◽

Mark Holmes ◽

Nicholas W. Morrell ◽

Sergei Danilov ◽

Paul N. Reynolds

Keyword(s):

Pulmonary Hypertension ◽

Gene Delivery ◽

Receptor Type ◽

Protein Receptor ◽