scholarly journals Serpiginoid choroiditis associated with presumed ocular tuberculosis

2019 ◽  
Vol 9 (2) ◽  
pp. 127 ◽  
Author(s):  
De-Kuang Hwang ◽  
Te-An Wang ◽  
Kang-Jung Lo ◽  
Shih-Jen Chen
Keyword(s):  
Ocular Tuberculosis ◽  
Presumed Ocular Tuberculosis

Clinical features and management of presumed ocular tuberculosis: A long-term follow-up cohort study in a tertiary referral center in Brazil

2021 ◽  
pp. 112067212110446
Author(s):  
Yuslay Fernández Zamora ◽  
Luciana Peixoto Finamor ◽  
Luci Meire P Silva ◽  
Denise S Rodrigues ◽  
Ricardo P Casaroli-Marano ◽  
...  
Keyword(s):  
Clinical Features ◽  
Oral Prednisone ◽  
Interferon Gamma Release Assay ◽  
Tertiary Referral ◽  
Ocular Tuberculosis ◽  
Tertiary Referral Center ◽  
Referral Center ◽  
Significant Difference ◽  
Presumed Ocular Tuberculosis

Purpose: To evaluate the clinical features and management of presumed ocular tuberculosis (OTB). Method: A prospective 3-year follow-up study of patients with ocular inflammation that performed Interferon-gamma release assay (IGRA) and tuberculin skin test (TST) was conducted in a tertiary referral center in Brazil. Patients with clinical signs highly suspect of OTB with a positive TST and/or IGRA with other causes ruled out were prescribed anti-tuberculosis therapy (ATT) during 9 months. Clinical features and treatment outcomes were recorded. Results: Seventy-two patients (mean age 48.3 ± 15.7 years) were included in the study, and most were female (65.3%, n = 47). Posterior uveitis (43.1%, n = 31) was the main clinical feature. Multifocal choroiditis (25%, n = 18) was the most common choroidal involvement. Concomitant oral prednisone (45.8%, n = 33) during ATT was associated with more recurrences ( p = 0.04). A significant difference ( p < 0.001) between initial and final best-corrected visual acuity after ATT conclusion was observed. Cure or remission was observed in 58 (85.3%) patients that completed follow-up ( n = 68). Conclusion: In our cohort some variation in demographics and ocular phenotypes of presumed OTB was observed. The high rates of cure or remission of our patients strongly support the ATT in presumed OTB. Oral corticosteroids during ATT were associated with higher recurrences rates.

scholarly journals Presumed ocular tuberculosis in the United Kingdom: a British Ophthalmological Surveillance Unit (BOSU) study

Eye ◽  
2020 ◽  
Vol 34 (10) ◽  
pp. 1835-1841 ◽  
Author(s):  
Katherine Shirley ◽  
Samir Dowlut ◽  
Julie Silvestri ◽  
Carlos Pavesio ◽  
Barny Foot
Keyword(s):  
United Kingdom ◽  
Ocular Tuberculosis ◽  
The United Kingdom ◽  
Surveillance Unit ◽  
Presumed Ocular Tuberculosis

scholarly journals Predictive factors for treatment failure in patients with presumed ocular tuberculosis in an area of low endemic prevalence

2015 ◽  
Vol 100 (3) ◽  
pp. 348-355 ◽  
Author(s):  
Rupesh Agrawal ◽  
Julio J Gonzalez-Lopez ◽  
João Nobre-Cardoso ◽  
Bhaskar Gupta ◽  
Robert Grant ◽  
...  
Keyword(s):  
Treatment Failure ◽  
Predictive Factors ◽  
Ocular Tuberculosis ◽  
Presumed Ocular Tuberculosis

Interferon Alpha for the Treatment of Cystoid Macular Edema Associated with Presumed Ocular Tuberculosis

2017 ◽  
Vol 33 (4) ◽  
pp. 304-312 ◽  
Author(s):  
Merih Oray ◽  
Sumru Onal ◽  
Gunay Uludag ◽  
Aylin Koc Akbay ◽  
Ilknur Tugal-Tutkun
Keyword(s):  
Macular Edema ◽  
Interferon Alpha ◽  
Cystoid Macular Edema ◽  
Ocular Tuberculosis ◽  
Presumed Ocular Tuberculosis

scholarly journals Unilateral choroidal tuberculoma as an initial manifestation of presumed ocular tuberculosis: a case report

2021 ◽  
Vol 80 (4) ◽  
Author(s):  
Juni Eyat Juni Ying ◽  
Chin Shi Tang ◽  
Maya Sapira Hanapi ◽  
Qi Zhe Ngoo ◽  
Wan Hazabbah Wan Hitam
Keyword(s):  
Case Report ◽  
Initial Manifestation ◽  
Ocular Tuberculosis ◽  
Presumed Ocular Tuberculosis ◽  
Choroidal Tuberculoma

Multifocal choroiditis and choroidal tuberculoma: Signs of presumed ocular tuberculosis

2021 ◽  
pp. 112067212110399
Author(s):  
Marta Belmonte Grau ◽  
Muxima Acebes García ◽  
Juan Jacobo González Guijarro
Keyword(s):  
Ocular Tissues ◽  
Swept Source ◽  
Radiographic Findings ◽  
Ocular Tuberculosis ◽  
Multifocal Choroiditis ◽  
Oral Steroids ◽  
Presumed Ocular Tuberculosis ◽  
Choroidal Tuberculoma

The diagnosis of OTB (Ocular tuberculosis) is usually difficult to make. Definitive diagnosis requires the identification of M. tuberculosis organisms in ocular tissues or fluids, but samples are often difficult to obtain, and biopsy may be hard to justify. We describe a 50-years-old Maghreb male, who presented a multifocal choroiditis associated with a choroidal tuberculoma on the left eye. Based on positive QuantiFERON-TB-Gold test and suggestive clinical and radiographic findings, a diagnosis of presumed ocular tuberculosis was made. Serial swept-source optical coherence tomography (SS-OCT) and widefield fundus retinographies during subsequent follow-up visits demonstrated the characterization of the atypical tuberculosis presentation and allowed the assessment of response to antitubercular therapy and oral steroids.

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