scholarly journals Electrical Stimulation of the Genioglossus in Patients with Residual Obstructive Sleep Apnea Post-UPPP Surgery

2015 ◽  
Vol 06 (02) ◽  
Author(s):  
Dong YB ◽  
Ding N
Keyword(s):  
Obstructive Sleep Apnea ◽  
Electrical Stimulation ◽  
Sleep Apnea ◽  
Obstructive Sleep ◽  
Stimulation Of

scholarly journals Electrical stimulation of the hypoglossal nerve: a potential therapy

2014 ◽  
Vol 116 (3) ◽  
pp. 337-344 ◽  
Author(s):  
Alan R. Schwartz ◽  
Philip L. Smith ◽  
Arie Oliven
Keyword(s):  
Obstructive Sleep Apnea ◽  
Electrical Stimulation ◽  
Sleep Apnea ◽  
Hypoglossal Nerve ◽  
Therapeutic Potential ◽  
Muscle Tone ◽  
Feasibility Trial ◽  
Airway Patency ◽  
Obstructive Sleep ◽  
Stimulation Of

Obstructive sleep apnea is characterized by recurrent episodes of pharyngeal collapse, which result from a decrease in pharyngeal dilator muscle tone. The genioglossus is a major pharyngeal dilator that maintains airway patency during sleep. Early studies in animal and humans have demonstrated that electrical stimulation of this muscle reduces pharyngeal collapsibility, increases airflow, and mitigates obstructive sleep apnea. These findings impelled the development of fully implantable hypoglossal nerve stimulating systems (HGNS), for which feasibility trial results are now available. These pilot studies have confirmed that hypoglossal nerve stimulation can prevent pharyngeal collapse without arousing patients from sleep. Potentially, a substantial segment of the patient population with obstructive sleep apnea can be treated with this novel approach. Furthermore, the feasibility trial findings suggest that the therapeutic potential of HGNS can be optimized by selecting patients judiciously, titrating the stimulus intensity optimally, and characterizing the underlying function and anatomy of the pharynx. These strategies are currently being examined in ongoing pivotal trials of HGNS.

Electrical stimulation of the whole hypoglossal nerve in patients with obstructive sleep apnea

2020 ◽  
Vol 24 (4) ◽  
pp. 1473-1480 ◽  
Author(s):  
A. Oliven ◽  
Y. Dotan ◽  
T. Golibroda ◽  
M. Somri ◽  
R. Oliven ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Electrical Stimulation ◽  
Sleep Apnea ◽  
Hypoglossal Nerve ◽  
Obstructive Sleep ◽  
Stimulation Of

scholarly journals Therapeutic Electrical Stimulation of the Hypoglossal Nerve in Obstructive Sleep Apnea

2001 ◽  
Vol 127 (10) ◽  
pp. 1216 ◽  
Author(s):  
Alan R. Schwartz ◽  
Marc L. Bennett ◽  
Philip L. Smith ◽  
Wilfried De Backer ◽  
Jan Hedner ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Electrical Stimulation ◽  
Sleep Apnea ◽  
Hypoglossal Nerve ◽  
Obstructive Sleep ◽  
Stimulation Of

Electrical stimulation of the hypoglossal nerve in the treatment of obstructive sleep apnea

2010 ◽  
Vol 14 (5) ◽  
pp. 299-305 ◽  
Author(s):  
Eric J. Kezirian ◽  
An Boudewyns ◽  
David W. Eisele ◽  
Alan R. Schwartz ◽  
Philip L. Smith ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Electrical Stimulation ◽  
Sleep Apnea ◽  
Hypoglossal Nerve ◽  
Obstructive Sleep ◽  
Stimulation Of
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