scholarly journals Benefits of Radiotherapy with Indigenous Tools Aiding Deep Inspiration Breath Holding Technique Compared to Free Breathing Technique among Breast Cancer Patients in Bangladesh

2021 ◽  
Vol 10 (03) ◽  
pp. 75-86
Author(s):  
Md. Arifur Rahman ◽  
Rajesh Balakrishnan ◽  
Md. Salim Reza ◽  
Qamruzzaman Chowdhury
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Free Breathing ◽  
Breath Holding ◽  
Deep Inspiration ◽  
Breast Cancer Patients

scholarly journals Is prone free breathing better than supine deep inspiration breath-hold for left whole-breast radiotherapy? A dosimetric analysis

2021 ◽  
Author(s):  
Xinzhuo Wang ◽  
Odile Fargier-Bochaton ◽  
Giovanna Dipasquale ◽  
Mohamed Laouiti ◽  
Melpomeni Kountouri ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Free Breathing ◽  
Breath Hold ◽  
Deep Inspiration ◽  
Breast Cancer Patients ◽  
Breast Radiotherapy ◽  
Deep Inspiration Breath Hold ◽  
Number Of Patients ◽  
Whole Breast Radiotherapy

Abstract Purpose The advantage of prone setup compared with supine for left-breast radiotherapy is controversial. We evaluate the dosimetric gain of prone setup and aim to identify predictors of the gain. Methods Left-sided breast cancer patients who had dual computed tomography (CT) planning in prone free breathing (FB) and supine deep inspiration breath-hold (DiBH) were retrospectively identified. Radiation doses to heart, lungs, breasts, and tumor bed were evaluated using the recently developed mean absolute dose deviation (MADD). MADD measures how widely the dose delivered to a structure deviates from a reference dose specified for the structure. A penalty score was computed for every treatment plan as a weighted sum of the MADDs normalized to the breast prescribed dose. Changes in penalty scores when switching from supine to prone were assessed by paired t-tests and by the number of patients with a reduction of the penalty score (i.e., gain). Robust linear regression and fractional polynomials were used to correlate patients’ characteristics and their respective penalty scores. Results Among 116 patients identified with dual CT planning, the prone setup, compared with supine, was associated with a dosimetric gain in 72 (62.1%, 95% CI: 52.6–70.9%). The most significant predictors of a gain with the prone setup were the breast depth prone/supine ratio (>1.6), breast depth difference (>31 mm), prone breast depth (>77 mm), and breast volume (>282 mL). Conclusion Prone compared with supine DiBH was associated with a dosimetric gain in 62.1% of our left-sided breast cancer patients. High pendulousness and moderately large breast predicted for the gain.

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