scholarly journals Analysis of Peripapillary Retinal Nerve Fiber Layer and Macular Volume in Patients with Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders, and Healthy Controls Using Spectral Domain Optical Coherence Tomography in a Turkish Cohort

2019 ◽  
Vol 25 (1) ◽  
pp. 26-31
Author(s):  
Ayşe İlksen Çolpak ◽  
Duygu Gülmez Sevim ◽  
Aslı Tuncer ◽  
Sevda Diker ◽  
Rana Karabudak ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Optical Coherence Tomography ◽  
Nerve Fiber ◽  
Neuromyelitis Optica ◽  
Retinal Nerve Fiber Layer ◽  
Healthy Controls ◽  
Neuromyelitis Optica Spectrum Disorders ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Spectrum Disorders

The Retinal Nerve Fiber Layer of Patients With Neuromyelitis Optica and Chronic Relapsing Optic Neuritis is More Severely Damaged than Patients With Multiple Sclerosis

2013 ◽  
Vol 33 (3) ◽  
pp. 220-224 ◽  
Author(s):  
Denis B. Bichuetti ◽  
André S. de Camargo ◽  
Alessandra B. Falcão ◽  
Fabiana F. Gonçalves ◽  
Ivan M. Tavares ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Optic Neuritis ◽  
Nerve Fiber ◽  
Neuromyelitis Optica ◽  
Retinal Nerve Fiber Layer ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Retinal Nerve Fiber

scholarly journals Time-Domain and Spectral-Domain Optical Coherence Tomography of Retinal Nerve Fiber Layer in MS Patients and Healthy Controls

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Alex P. Lange ◽  
Reza Sadjadi ◽  
Jameelah Saeedi ◽  
Janette Lindley ◽  
Fiona Costello ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Time Domain ◽  
Disease Duration ◽  
Healthy Controls ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
History Of

Objective. The aim of this study was to compare retinal nerve fiber layer thickness (RNFLT) between spectral-domain (SD-) and time-domain optical coherence tomography (TD-OCT) in MS patients and healthy controls (HC). Furthermore, RNFLT between MS eyes with and without optic neuritis (ON) and HC should be explored. Finally, the relationship between RNFLT, disease duration, EDSS, and disease modifying therapy (DMT) should be established.Design. Prospective, cross-sectional study.Participants. 28 MS patients and 35 HC.Methods. Both groups underwent TD- and SD-OCT measurements. RFNLT was correlated between the two machines and between MS eyes with and without ON and HC. Furthermore, RNFLT was correlated to disease duration, EDSS and DMT.Results. A strong correlation (Pearson’sr=0.921,P<0.001), but a statistically significant difference of 2 μm (P<0.001), was found between the two devices. RNFLT was significantly different between MS eyes with history of ON (mean RFNLT (SD) 72.21 μm (15.83 μm)), MS eyes without history of ON 93.03 μm (14.25 μm), and HC 99.07 μm (7.23 μm) (P<0.001).Conclusions. The measurements between different generation of OCT machines are not interchangeable, which should be taken into account if comparing results between different machines and switching OCT machine in longitudinal studies.

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