scholarly journals Quality of Life in Patients with Drug Resistant Epilepsy

2019 ◽  
Vol 25 (3) ◽  
pp. 159-163
Author(s):  
Hari Krishan Aggarwal ◽  
Deepak Jain ◽  
Avina Bishnoi
Keyword(s):  
Quality Of Life ◽  
Drug Resistant ◽  
Drug Resistant Epilepsy

Fifteen-minute consultation: When medicines don’t work—the child with poorly controlled seizures

2018 ◽  
Vol 104 (3) ◽  
pp. 135-140
Author(s):  
Pooja Harijan ◽  
Arnab Kumar Seal ◽  
Manish Prasad ◽  
William P Whitehouse
Keyword(s):  
Quality Of Life ◽  
Epilepsy Surgery ◽  
Drug Resistant ◽  
Algorithmic Approach ◽  
Life Management ◽  
Drug Resistant Epilepsy

Drug-resistant epilepsy (DRE) occurs in 20%–30% of children with epilepsy with significant impact on their quality of life. Management of this group of children has greatly improved in the recent years with streamlining of epilepsy surgery services and associated quaternary multimodal evaluation. This article provides a review of DRE in children and management based on recent evidence and published opinion. We have also presented an algorithmic approach to the child with possible DRE.

Care-related quality of life in caregivers of children with drug-resistant epilepsy

2018 ◽  
Vol 265 (10) ◽  
pp. 2221-2230 ◽  
Author(s):  
Puneet Jain ◽  
◽  
Jhananiee Subendran ◽  
Mary Lou Smith ◽  
Elysa Widjaja
Keyword(s):  
Quality Of Life ◽  
Drug Resistant ◽  
Related Quality ◽  
Drug Resistant Epilepsy

scholarly journals Characteristics associated with quality of life among people with drug-resistant epilepsy

2017 ◽  
Vol 264 (6) ◽  
pp. 1174-1184 ◽  
Author(s):  
Leone Ridsdale ◽  
◽  
Gabriella Wojewodka ◽  
Emily Robinson ◽  
Sabine Landau ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Drug Resistant ◽  
Drug Resistant Epilepsy

Treating Drug-resistant Epilepsy – Why are we Waiting?

2015 ◽  
Vol 10 (2) ◽  
pp. 171
Author(s):  
Paul Boon ◽  
Philippe Ryvlin ◽  
James W Wheless ◽  
Kensuke Kawai ◽  
◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psychiatric Disease ◽  
Drug Resistant ◽  
Treatment Gap ◽  
Health Service Provision ◽  
Adequate Treatment ◽  
Seizure Reduction ◽  
Number Of Patients ◽  
Drug Resistant Epilepsy

Drug-resistant epilepsy (DRE) has been defined by the ad hoc Task Force of the International League Against Epilepsy (ILAE) Commission on Therapeutic Strategies as the failure of two appropriately chosen and tolerated anti-epileptic drugs (AEDs) (whether as monotherapy or in combination) to control seizures when used for an adequate period of time. The difference between the number of patients with DRE and the number of these patients who do not get access to adequate treatment is defined as the ‘treatment gap’, which is considered to be substantial. There are multiple possible causes that underlie the treatment gap in DRE: economic costs, natural history of epilepsy, deficiencies in health service provision, social stigma and other as yet unidentified causes. Factors affecting quality of life in DRE include depression and anxiety, raised risk of mortality and morbidity, increased healthcare utilisation and increased risk of adverse events with long- term use of AEDs, cognitive and memory impairment, seizure-related injuries, impaired ability to achieve educational and vocational goals, to drive, establish families and benefit from social relationships. Among the reasons for the greater risk of premature death are the raised risk of suicide in those patients with comorbid psychiatric disease and the increased incidence of sudden unexpected death among those with epilepsy. Managing epilepsy well involves more than just seizure reduction and when freedom from seizures cannot be achieved, addressing quality of life is likely to be more beneficial than interventions aimed at seizure reduction alone. Options exist for patients with DRE who are not candidates for epilepsy surgery, including dietary treatments, further attempts with AEDs and non-pharmacological interventions with devices. Further, non-invasive modalities are emerging, creating a more hopeful picture that the treatment gap for patients with DRE may be narrowed or even closed.

scholarly journals Long-Term Impact in the Quality of Life of Patients with Drug-Resistant Epilepsy That Use Cannabidiol

2021 ◽  
Vol 12 (04) ◽  
pp. 103-113
Author(s):  
Gabriela Pesántez Ríos ◽  
Ignacio Pascual Pascual ◽  
Ximena Pesántez Ríos ◽  
Luciana Armijos ◽  
Estefanía Chediak ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Drug Resistant ◽  
Drug Resistant Epilepsy ◽  
Long Term Impact

scholarly journals Positive illusions determine quality of life in drug‐resistant epilepsy

Epilepsia ◽  
2020 ◽  
Vol 61 (3) ◽  
pp. 539-548 ◽  
Author(s):  
Sarah J. Wilson ◽  
Genevieve Rayner ◽  
Jessamae Pieters
Keyword(s):  
Quality Of Life ◽  
Drug Resistant ◽  
Positive Illusions ◽  
Drug Resistant Epilepsy
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