Neo-Darwinian evolutionary theory explains how the appearance of purposive design in the adaptations of living organisms can have come about without their intentionally being designed. The explanation relies crucially on the possibility of certain
physical processes
: mainly,
gene replication
and
natural selection
. In this paper, I show that for those processes to be possible without the
design of biological adaptations
being encoded in the laws of physics, those laws must have certain other properties. The theory of what these properties are is not part of evolution theory proper, yet without it the neo-Darwinian theory does not fully achieve its purpose of explaining the appearance of design. To this end, I apply constructor theory's new mode of explanation to express exactly within physics the appearance of design, no-design laws, and the logic of self-reproduction and natural selection. I conclude that self-reproduction, replication and natural selection are possible under no-design laws, the only non-trivial condition being that they allow
digital information
to be physically instantiated. This has an exact characterization in the constructor theory of information. I also show that under no-design laws an accurate replicator
requires
the existence of a ‘vehicle’ constituting, together with the replicator, a self-reproducer.