scholarly journals MINI REVIEW ON SELECTION OF CHROMATOGRAPHIC TECHNIQUES FOR THERAPEUTIC DRUG MONITORING

2021 ◽  
Vol 10 (2b) ◽  
pp. 44-51
Author(s):  
Simranjeet Kaur ◽  
Gourav Kalra
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Drug Monitoring ◽  
Therapeutic Drug ◽  
Chromatographic Techniques ◽  
Selection Of

Therapeutic Drug Monitoring in Neonates: Problems and Issues

1988 ◽  
Vol 22 (4) ◽  
pp. 317-323 ◽  
Author(s):  
Peter Gal
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Drug Concentration ◽  
Drug Monitoring ◽  
Pharmacokinetic Parameters ◽  
Therapeutic Drug ◽  
Plasma Drug ◽  
Potential Applications ◽  
Intensive Care Nursery ◽  
Effective Use ◽  
Selection Of

Therapeutic drug monitoring has been applied in several patient populations to promote safer, more effective use of drugs. The development of therapeutic ranges allows clinicians to aim for a plasma drug concentration that is usually safe and effective, and calculation of specific pharmacokinetic parameters allows selection of doses that will achieve the desired plasma concentration. This concept certainly holds true in the intensive care nursery; however, the intensity of monitoring in this setting provides opportunities for far broader application of the information obtained from drug concentration monitoring. This review provides an overview of the complexity of and potential applications for therapeutic drug monitoring in neonates based on literature and clinical experience.

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