scholarly journals Basaloid squamous cell carcinoma of the uterine cervix coexisting with undifferentiated sarcoma

2020 ◽  
Vol 19 (4) ◽  
pp. 192-194
Author(s):  
Magdalena Lemm ◽  
Łukasz Słowik ◽  
Bartosz Cichoń ◽  
Michał Poński ◽  
Łukasz Szwaczka ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Uterine Cervix ◽  
Basaloid Squamous Cell Carcinoma ◽  
Undifferentiated Sarcoma ◽  
Basaloid Squamous

Basaloid Squamous Cell Carcinoma of the Uterine Cervix: Report of a Case With Molecular Analysis

2021 ◽  
pp. 106689692199713
Author(s):  
Jijgee Munkhdelger ◽  
Tomoko Shimooka ◽  
Yoshinori Koyama ◽  
Sadakatsu Ikeda ◽  
Yoshiki Mikami ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Uterine Cervix ◽  
Pik3ca Mutation ◽  
Biological Behavior ◽  
Basaloid Squamous Cell Carcinoma ◽  
Surgical Specimen ◽  
Molecular Alterations ◽  
Basaloid Squamous

There is a lack of knowledge about molecular alterations in basaloid squamous cell carcinoma (BSCC) of the uterine cervix. A 72-year-old woman with a history of previous subtotal hysterectomy and current vaginal bleeding was referred to our hospital. Initially, adenoid cystic carcinoma (ACC) was diagnosed upon cervical cytology and biopsy. Chest imaging showed multiple metastatic lesions in both lungs. The surgical specimen showed BSCC with diffuse p16 immunoreactivity and negativity for S-100, c-kit, and neuroendocrine markers. There was a focal minor ACC component, which could have explained the previous cytology and biopsy diagnosis. Next-generation sequencing with two different panels showed coexisting PIK3CA mutation and NTRK2 fusion with 10 additional variants of unknown significance ( ATR, DAXX, FAM123B, JAK1, KEL, MLL2, NOTCH2, PALB2, POLD1, POLE). The MYB gene fusions were not identified. The patient received chemotherapy with TRK inhibitor larotrectinib and carboplatin, which caused shrinkage of metastatic lung nodules. This is the first report of cervical BSCC with extensive molecular workup, which detected multiple genetic events, including targetable ones, which are potentially implicated in the development of a tumor. The accumulation of data and further studies on this tumor are necessary to define its diagnostic criteria and its clinical and biological behavior.

scholarly journals Pure Basaloid Squamous Cell Carcinoma of the Uterine Cervix: A Case Report

2009 ◽  
Vol 24 (3) ◽  
pp. 542 ◽  
Author(s):  
Yong Soon Kwon ◽  
Yong Man Kim ◽  
Ga Won Choi ◽  
Young Tak Kim ◽  
Joo-Hyun Nam
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Uterine Cervix ◽  
Basaloid Squamous Cell Carcinoma ◽  
Basaloid Squamous

Basaloid squamous cell carcinoma of the uterine cervix: Cytological and histological features

2015 ◽  
Vol 43 (12) ◽  
pp. 993-995 ◽  
Author(s):  
Rafael Martínez-Girón ◽  
Santiago Martínez-Torre ◽  
and Joaquín Mosquera-Martínez
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Uterine Cervix ◽  
Basaloid Squamous Cell Carcinoma ◽  
Histological Features ◽  
Basaloid Squamous

scholarly journals Basaloid squamous cell carcinoma of uterine cervix in a young adult - A case report

2019 ◽  
Vol 12 (12) ◽  
Author(s):  
Angel Yordanov ◽  
Stanislav Slavchev ◽  
Vasil Nanev ◽  
Denislava Ivanova ◽  
Momchil Ivanov ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Young Adult ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Uterine Cervix ◽  
Basaloid Squamous Cell Carcinoma ◽  
Basaloid Squamous

scholarly journals Pulmonary metastasectomy for esophageal basaloid squamous cell carcinoma component at 66 months after esophagectomy

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Kumiko Sekiguchi ◽  
Takeshi Matsutani ◽  
Tsutomu Nomura ◽  
Nobutoshi Hagiwara ◽  
Akihisa Matsuda ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Pulmonary Metastasectomy ◽  
Basaloid Squamous Cell Carcinoma ◽  
Basaloid Squamous

scholarly journals Cutaneous metastasis from esophageal basaloid squamous cell carcinoma: A case report

2021 ◽  
Vol 80 ◽  
pp. 105621
Author(s):  
Fumitaka Endo ◽  
Yuji Akiyama ◽  
Masazumi Onishi ◽  
Noriyuki Uesugi ◽  
Tamotsu Sugai ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cutaneous Metastasis ◽  
Basaloid Squamous Cell Carcinoma ◽  
Basaloid Squamous
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