scholarly journals Interferon Gamma Release Assay for the Identification of Latent Tuberculosis Infection in Rural and Remote Settings

2021 ◽  
Vol 1 (4) ◽  
Author(s):  
Kendra Brett ◽  
Melissa Severn

There is a lack of evidence on the clinical utility of the interferon gamma release assay for identifying latent tuberculosis infection in rural and remote settings. In remote Indigenous communities with known history of bacillus Calmette-Guérin vaccination, more positive tests results were reported with the tuberculin skin test than with the interferon gamma release assay.

2021 ◽  
Vol 1 (5) ◽  
Author(s):  
Kendra Brett ◽  
Melissa Severn

In people who have been vaccinated with Bacillus Calmette-Guérin, the interferon gamma release assay appears to be related to fewer diagnoses for latent tuberculosis infection, fewer prescriptions of preventive tuberculosis therapy, and no difference in the number of active TB cases compared to the tuberculin skin test (findings based on 1 [non-randomized study] of low quality). No evidence-based guidelines were found regarding the identification of latent tuberculosis infection in people with previous Bacillus Calmette-Guérin vaccination.


Sign in / Sign up

Export Citation Format

Share Document