scholarly journals A Rare Infection Factor in a Patient with Multiple Nodules During The COVID-19 Pandemic Period: Actinomycosis Odontoliticus

Author(s):  
Betül İkbal Doğan ◽  
Ceyda Anar ◽  
Bunyamin Sertogullarindan ◽  
Onur Turan

Pulmonary actinomycosis has been reported to account for 15% of all cases of actinomycosis, and pulmonary Actinomyces odontolyticus is particularly rare. Actinomycosis is a chronic granulomatous infection that often occurs in immunocompromised conditions, but it can also affect healthy people.Here, we present a case in which we diagnosed an immunocompetent 33-year-old female patient with bronchoalveolar lavage (BAL) by bronchoscopy, which is characterized by nodules with ground glass density in bilateral lung caused by A. odontolyticus due to a dental abscess. Bilateral nodular infiltrates made us think of metastatic lung disease; We assessed the patıent in terms of COVID-19 pneumonıa as we are in the perıod of pandemia.

2016 ◽  
Vol 25 (139) ◽  
pp. 97-98 ◽  
Author(s):  
Vikas Pilaniya ◽  
Kamal Gera ◽  
Shekhar Kunal ◽  
Ashok Shah

CHEST Journal ◽  
1991 ◽  
Vol 100 (6) ◽  
pp. 1743-1744
Author(s):  
Petre C. Hill ◽  
Monte A. Herman ◽  
Prashant Kumar Rohatgi

2009 ◽  
Vol 35 (5) ◽  
pp. 480-483 ◽  
Author(s):  
Chandramani Panjabi ◽  
Sandeep Sahay ◽  
Ashok Shah

Pulmonary cavitation is rather uncommon in patients with sarcoidosis, and aspergilloma is even more uncommon in such cases. Here, we present the case of a 63-year-old female patient with cavitary lung disease who had been under treatment for TB for 9 months. A diagnosis of pulmonary sarcoidosis was established based on the fiberoptic bronchoscopy finding of noncaseating granuloma. Treatment with corticosteroids led to a dramatic improvement in symptoms. While under treatment for sarcoidosis, the patient developed an aspergilloma. She presented immediate skin test reactivity to Aspergillus fumigatus, as well as positivity for A. fumigatus serum precipitins. This is the first reported case of aspergilloma formation in a patient with cavitary sarcoidosis in India.


2021 ◽  
Author(s):  
Junyu Liang ◽  
Heng Cao ◽  
Yinuo Liu ◽  
Bingjue Ye ◽  
Yiduo Sun ◽  
...  

Abstract Background: Interstitial lung disease (ILD) and its rapid progression (RP) were main contributors to unfavorable outcome of idiopathic inflammatory myopathy (IIM) patients. This study aimed at identifying the clinical value of PET/CT scan in IIM-ILD patients as well as constructing a predicting model for RP-ILD.Methods: Adult IIM-ILD patients who were hospitalized at four divisions of the First Affiliated Hospital, Zhejiang University School of Medicine (FAHZJU) from Jannuary 1st 2017 to December 31st 2020 were reviewed. PET/CT scan as well as other factors of patients who met the inclusion and exclusion criteria were collected and analyzed.Results: A total of 61 IIM-ILD patients were finally enrolled into this study. Twenty-one patients (34.4%) developed RP-ILD and 24 patients (39.3%) died in follow-up. After false discovery rate (FDR) correction, percent-predicted diffusing capacity of the lung for carbon monoxide (DLCO%, P=0.014), bilateral lung mean standard uptake value (SUVmean, P=0.014) and abnormal mediastinal lymph node (P=0.045) were significantly different in comparison between RP-ILD and non-RP-ILD groups. A “DLM” model was hereby established by including the above three values to predict RP-ILD with a cutoff value of ≥2 and an area under the curve (AUC) of 0.905. Higher bilateral lung SUVmean (P=0.019) and spleen SUVmean (P=0.011) were observed in IIM-ILD patients who died within three months, and a moderate correlation was recognized between the two values. Conclusions: Elevated bilateral lung SUVmean and abnormal mediastinal lymph node were associated with RP-ILD in IIM-ILD patients. The “DLM” model was valuable in predicting RP-ILD and demanded further evaluation.


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