Sneddon’s Syndrome: a case report

Context: Sneddon’s Syndrome is a small and medium caliber arteries vasculopathy, characterized by concomitant occurrence of cerebrovascular disease and livedo reticularis. It’s a rare disorder, more prevalent in women. In up to 80% of cases, positive antiphospholipid’s antibodies are found. Case report: A 28-year-old woman was admitted to Hospital das ClínicasUFTM on May 21th, 2020, referred under suspicion of stroke with ictus on May 19th, 2020. The exam revealed left hemiparesis, anomic afasia and livedo reticularis on her thighs and thorax. She denied having comorbidities or previous episodes of thromboembolism. She had taken combined oral contraceptive for eleven years, having changed medication a year ago. In the cranial angioresonance exam, acute ischemia was confirmed in addition to moderate microangiopathy and an area of encephalomalacia. In the etiological investigation, HEP-2 positive antibody (antinuclear factor in a fine dotted nuclear pattern) was detected. She was discharged with a prescription of 100 mg of acetylsalicylic acid daily, maintained as a form of secondary prophylaxis. Conclusions: The case illustrates the importance of a thorough physical examination and anamnesis in cerebrovascular disease patients, in order to get a accurate aetiological diagnosis of these diseases, enabling a more effective prognostic evaluation and secondary prophylaxis.