Post-traumatic Stress Disorder and Comorbid Psychotic Disorder: Electroconvulsive Therapy Response in Two Patients

2013 ◽  
Vol 23 (4) ◽  
pp. 373-377
Author(s):  
Barbaros Ozdemir ◽  
Beyazit Garip ◽  
Taner Oznur ◽  
Murat Erdem ◽  
Suleyman Akarsu
Keyword(s):  
Psychotic Disorder ◽  
Electroconvulsive Therapy ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Therapy Response ◽  
Post Traumatic Stress ◽  
Post Traumatic

scholarly journals Electroconvulsive Therapy with a Memory Reactivation Intervention for Post-Traumatic Stress Disorder: A Randomized Controlled Trial

2020 ◽  
Author(s):  
Victor M. Tang ◽  
Kathleen Trought ◽  
Kristina M. Gicas ◽  
Mari Kozak ◽  
Sheena A. Josselyn ◽  
...  
Keyword(s):  
Heart Rate ◽  
Electroconvulsive Therapy ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Traumatic Memory ◽  
Post Traumatic Stress ◽  
Memory Reactivation ◽  
Link Type ◽  
Post Traumatic

AbstractIntroductionPost-traumatic Stress Disorder (PTSD) often does not respond to available treatments. Memories are vulnerable to disruption during reconsolidation, and electroconvulsive therapy (ECT) has amnestic effects. We sought to exploit this phenomenon as a potential treatment for PTSD with a clinical trial of patients with PTSD receiving ECT.MethodsTwenty-eight participants with severe depression with comorbid PTSD referred for ECT treatment were randomly assigned to reactivation of a traumatic or non-traumatic memory using script driven imagery prior to each ECT treatment. Primary outcomes were change in scores on the Modified PTSD Symptom Scale - Self Report (MPSS-SR) and the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5). Assessments were completed by blinded raters. Secondary outcomes included a comparison of the change in heart rate while listening to the script.ResultsTwenty-five patients who completed a post-ECT assessment were included in the analysis. No significant group differences were found in the MPSS-SR or CAPS-5 scores from pre-ECT to post-ECT or 3-month follow-ups. However, both groups improved at post-ECT and 3-month follow up. Partial eta squared estimates of effect size showed large effect sizes for all outcomes (η2 > 0.13). Changes in heart rate were not significantly different between groups or over time.ConclusionsIn this RCT, ECT paired with pre-treatment traumatic memory reactivation was not more effective for treating PTSD symptoms than ECT alone. While our primary hypothesis was not supported, our data provides further support for the efficacy of ECT for improving symptoms of PTSD with comorbid depression.ClinicalTrials.govhttps://clinicaltrials.gov/ct2/show/NCT04027452Identifier: NCT04027452

scholarly journals Predictive validity of the Trauma Screening Questionnaire in detecting post-traumatic stress disorder in patients with psychotic disorders

2015 ◽  
Vol 206 (5) ◽  
pp. 408-416 ◽  
Author(s):  
Paul A. J. M. de Bont ◽  
David P. G. van den Berg ◽  
Berber M. van der Vleugel ◽  
Carlijn de Roos ◽  
Ad de Jongh ◽  
...  
Keyword(s):  
Psychotic Disorder ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Psychotic Disorders ◽  
Screening Tool ◽  
Stress Disorder ◽  
Trauma Exposure ◽  
Post Traumatic Stress ◽  
Screening Questionnaire ◽  
Post Traumatic

BackgroundPost-traumatic stress disorder (PTSD) is highly prevalent in patients with a psychotic disorder. Because a PTSD diagnosis is often missed in patients with psychosis in routine care, a valid screening instrument could be helpful.AimsTo determine the validity of the Trauma Screening Questionnaire (TSQ) as a screening tool for PTSD among individuals with psychotic disorders.MethodAmong 2608 patients with a psychotic disorder, the rate of trauma exposure was determined and the TSQ was administered to screen for PTSD. PTSD status was verified in 455 patients using the Clinician-Administered PTSD Scale (trial registration: ISRCTN 79584912).ResultsTrauma exposure was reported by 78.2% of the 2608 patients. PTSD prevalence was estimated at 16% (95% CI 14.6–17.4%) compared with 0.5% reported in the patients' clinical charts. A TSQ cut-off score of six predicted PTSD with 78.8% sensitivity, 75.6% specificity, 44.5% correct positives and 93.6% correct negatives.ConclusionsThe TSQ seems to be a valid screening tool for PTSD in patients with a psychotic disorder.

scholarly journals Risk of non-affective psychotic disorder and post-traumatic stress disorder by refugee status in Sweden

2019 ◽  
Vol 74 (3) ◽  
pp. 276-282
Author(s):  
Arvinder K Duggal ◽  
James B Kirkbride ◽  
Christina Dalman ◽  
Anna-Clara Hollander
Keyword(s):  
Psychiatric Disorders ◽  
Psychotic Disorder ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Post Traumatic Stress ◽  
Refugee Status ◽  
Increased Risk ◽  
Icd 10 ◽  
Post Traumatic

BackgroundRefugees have different experiences of obtaining a refugee status, however it remains unclear if this affects their risk of psychiatric disorders. The aim of this study was to investigate whether risk for non-affective psychotic disorder (NAPD) and post-traumatic stress disorder (PTSD) differs between quota refugees (resettled from refugee camps) and non-quota refugees (former asylum seekers).MethodA register-based cohort with a sample size of 52 561 refugees in Sweden starting 1 January 1997 ending 31 December 2011. Exposure: refugee status (quota or non-quota refugees). Cox regression models estimated adjusted HRs with 95% CIs for NAPD (International Classification of Diseases, Tenth Revision (ICD-10), F20–29) and PTSD (ICD-10, F43.1) by refugee status.ResultsThere were more non-quota refugees (77.0%) than quota refugees (23.0%). In total we identified 401 cases of NAPD, 1.0% among quota refugees and 0.7% among non-quota refugees, and 1070 cases of PTSD, 1.9% among quota refugees and 2.1% among non-quota refugees. Male quota refugees were at increased risk for NAPD compared with male non-quota refugees (HRmale=1.41, 95% CI 1.09 to 1.82 and HRfemale=0.65, 95% CI 0.42 to 1.00). All quota refugees were at a reduced risk of PTSD compared with non-quota refugees (HR=0.74, 95% CI 0.64 to 0.87).ConclusionsThis study suggests that risk of NAPD and PTSD varies for quota and non-quota refugees, highlighting the possibility that different experiences of the migration process differentiate the risk of psychiatric disorders among refugees.

Hallucinations in Adolescents With Post-Traumatic Stress Disorder and Psychotic Disorder

2007 ◽  
Vol 15 (1) ◽  
pp. 44-48 ◽  
Author(s):  
James Graham Scott ◽  
Barry Nurcombe ◽  
Judith Sheridan ◽  
Margaret McFarland
Keyword(s):  
Psychotic Disorder ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Post Traumatic Stress ◽  
Post Traumatic
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