scholarly journals Comparison of Pulmonary Functions at Onset of Ventilatory Insufficiency in Patients With Amyotrophic Lateral Sclerosis, Duchenne Muscular Dystrophy, and Myotonic Muscular Dystrophy

2016 ◽  
Vol 40 (1) ◽  
pp. 74 ◽  
Author(s):  
Han Eol Cho ◽  
Jang Woo Lee ◽  
Seong Woong Kang ◽  
Won Ah Choi ◽  
Hyeonjun Oh ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Pulmonary Functions ◽  
Ventilatory Insufficiency ◽  
Myotonic Muscular Dystrophy ◽  
Lateral Sclerosis

Carbonic anhydrase III in serum in muscular dystrophy and other neurological disorders: relationship with creatine kinase

1991 ◽  
Vol 37 (1) ◽  
pp. 36-39 ◽  
Author(s):  
Mitsuhlro Ohta ◽  
Yasuko Itagaki ◽  
Nobuyukl Itoh ◽  
Kyozo Hayashi ◽  
Hirosh Nishitani ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Creatine Kinase ◽  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Carbonic Anhydrase ◽  
Neurological Disorders ◽  
Muscular Atrophy ◽  
Carbonic Anhydrase Iii ◽  
Severity Of The Disease ◽  
Lateral Sclerosis

Abstract We measured with a radioimmunoassay the concentrations of carbonic anhydrase III (CA-III, EC 4.2.1.1) in sera from 68 patients with muscular dystrophy, 10 carriers of Duchenne muscular dystrophy (DMD), and 63 patients with other neurological disorders. The values obtained were compared with those for creatine kinase (CK, EC 2.7.3.2). Serum CA-III was strikingly increased in patients with DMD (mean, 274.4 micrograms/L) and congenital (Fukuyama-type) (182.8 micrograms/L) and limb-girdle (203.7 micrograms/L) dystrophies and positively correlated with the activities of CK in patients with DMD. CA-III concentration decreased with the subjects' age and the severity of the disease, similar to the tendency observed between age or severity and the concentration of CK. We found moderately increased CA-III in patients with polymyositis, myotonic dystrophy, amyotrophic lateral sclerosis, spinal progressive muscular atrophy, or Kugelberg-Welander disease and in carriers of DMD.

scholarly journals Errata: Measuring Disease Severity in Duchenne and Becker Muscular Dystrophy

2011 ◽  
Vol 1 (2) ◽  
Author(s):  
Melinda F. Davis ◽  
Katalin H. Scherer ◽  
Timothy M. Miller ◽  
F. John Meaney
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Muscular Dystrophy ◽  
Disease Severity ◽  
Muscle Weakness ◽  
Respiratory Function ◽  
Rating Scale ◽  
Becker Muscular Dystrophy ◽  
Progressive Muscle Weakness ◽  
Lateral Sclerosis ◽  
Disease Specific

Reports an error in Davis et al. (2010).  The functional motor scale used in Davis et al. (2010) was the EK (Egen Klassifikation) Scale, rather than the Amyotrophic Lateral Sclerosis Functional Rating Scale (Steffensen et al., 2002; Cedarbaum & Stambler, 1997).  Both scales are 10-item, disease-specific measures that assess mobility and respiratory function in individuals with progressive muscle weakness.  This error does not change the conclusions. DOI:10.2458/azu_jmmss_v1i2_davis

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