Giant Pleomorphic Adenoma of the Parotid gland- A Case Report

10.5580/2a92 ◽  
2012 ◽  
Vol 14 (1) ◽  
Keyword(s):  
Case Report ◽  
Parotid Gland ◽  
Pleomorphic Adenoma

Myoepithelial Carcinoma ex Pleomorphic Adenoma: Rare Case Report with Clinicopathologic and Immunohistochemical Features

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S86-S87
Author(s):  
M Khazaeli ◽  
Z Kamaluddin ◽  
M Taherian
Keyword(s):  
Case Report ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Nasal Passage ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
Sublingual Gland ◽  
Myoepithelial Carcinoma ◽  
Minor Salivary Glands ◽  
Myoepithelial Differentiation ◽  
The Right

Abstract Introduction/Objective Myoepithelial carcinoma is identified by nearly exclusive myoepithelial differentiation and evidence of malignancy. It may arise de novo or in preexisting benign tumors including pleomorphic adenoma and benign myoepithelioma. It occurs most commonly in the parotid gland followed by submandibular glands, minor salivary glands, and occasionally in the sublingual gland. Nasopharyngeal origin has been rarely reported. Methods/Case Report An afebrile 19-year-old female presented to the emergency department with persistent facial pressure, otalgia (right side greater than left side), rhinorrhea, and several episodes of epistaxis. One month before, she has been treated with Amoxicillin for three days with no relief, where Augmentin started for her for five days. About four days prior presentation, she was placed on Prednisone and Cefdinir. Over the next several days, she began having throat pain with difficulty swallowing. Routine blood work revealed a leukocytosis of 14.2 with normal differentiation. CT of the neck showed a large soft tissue mass centered at the right nasopharynx. Flexible nasal endoscopy performed bilaterally to reveal the nasopharynx is entirely obstructed with a lobulated mass filling the nasopharynx. On the right side, it extends into the posterior nasal passage filling the sphenoethmoid recess and the posterior floor of the nasal passage. Outpatient biopsy from nasopharynx mass is also performed. Results (if a Case Study enter NA) Mass biopsy reveals a mucinous and chondromyxoid background with mixed epithelial and myoepithelial differentiation. The is squamous metaplasia of myoepithelial cells and prominent mitotic activity and apoptotic activity. Immunohistochemistry was positive for CK5/6, calponin, BCL2, SMA, BerEp4, Sox10, and a proliferative index up to 40%. Based on this information Myoepithelial Carcinoma ex-pleomorphic adenoma of the nasopharynx is the diagnosis. Conclusion Carcinoma ex pleomorphic adenoma is usually a high-grade malignancy. It occurs most commonly in the parotid gland, followed by submandibular glands, minor salivary glands, and occasionally in the sublingual gland. Our case is one of the few cases of myoepithelial carcinoma arising in nasopharyngeal pleomorphic adenoma.

scholarly journals Pleomorphic Adenoma of the Parotid Gland: A Case Report

2021 ◽  
Vol 5 (3) ◽  
pp. CR6-CR9
Author(s):  
Rajesh Gupta ◽  
Preety Gupta ◽  
Shivani Gupta ◽  
Sumit Garg
Keyword(s):  
Case Report ◽  
Parotid Gland ◽  
Head And Neck ◽  
Pleomorphic Adenoma

Salivary organ tumors are uncommon, including under 3 % of all neoplasia of head and neck district. Pleomorphic adenoma is the most well-known salivary organ tumor, representing 60-80% of amiable tumors of salivary organs. Generally they are found as singular one-sided, firm and portable, effortless, moderate developing mass. The board includes careful resection by shallow or absolute parotidectomy.

scholarly journals Giant pleomorphic adenoma of the parotid gland extending to the parapharyngeal space: A rare case report

2018 ◽  
Vol 0 ◽  
pp. 1
Author(s):  
Fahmi H. Kakamad ◽  
Shakhawan M. Ali ◽  
Imad J. Habibullah ◽  
Payman Kh. Mahmud
Keyword(s):  
Case Report ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Rare Case ◽  
Parapharyngeal Space ◽  
Rare Case Report

scholarly journals An ulcerated giant pleomorphic adenoma of the parotid gland – A case report

2016 ◽  
Vol 17 (2) ◽  
pp. 111-114 ◽  
Author(s):  
Santosh K. Swain ◽  
Mahesh C. Sahu ◽  
Satyajit Mishra
Keyword(s):  
Case Report ◽  
Parotid Gland ◽  
Pleomorphic Adenoma

Squamous-cell carcinoma after radiotherapy for a recurring pleomorphic adenoma of the parotid gland: A case report

2016 ◽  
Vol 28 (2) ◽  
pp. 152-155
Author(s):  
R.H. Khonsari ◽  
C. Bertoïa-Caufourier ◽  
G. Murcier ◽  
G. Hervé ◽  
A. Assouline ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Parotid Gland ◽  
Cell Carcinoma ◽  
Pleomorphic Adenoma ◽  
Squamous Cell

scholarly journals Giant Pleomorphic Adenoma of Parotid Gland; A Case Report.

2001 ◽  
Vol 94 (11) ◽  
pp. 1013-1017
Author(s):  
Michiya KOSAKA ◽  
Yasutaka HORI ◽  
Yoko HAGIIKE ◽  
Hirofumi AKAGI
Keyword(s):  
Case Report ◽  
Parotid Gland ◽  
Pleomorphic Adenoma
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