CROHN'S DISEASE AND THE LARGE BOWEL

1972 ◽  
Vol 2 (19) ◽  
pp. 1043-1044
Author(s):  
Diane Mege ◽  
Willem A. Bemelman ◽  
Yves Panis ◽  
Michael R.B. Keighley

1976 ◽  
Vol 11 (5) ◽  
pp. 433-436 ◽  
Author(s):  
Jean K. Ritchie ◽  
J. E. Lennard-Jones

2015 ◽  
Vol 81 (10) ◽  
pp. 1021-1027 ◽  
Author(s):  
Zhobin Moghadamyeghaneh ◽  
Joseph C. Carmichael ◽  
Steven D. Mills ◽  
Alessio Pigazzi ◽  
Michael J. Stamos

There is limited data regarding outcomes of bowel resection in patients with Crohn's disease. We sought to investigate complications of such patients after bowel resection. The Nationwide Inpatient Sample databases were used to examine the clinical data of Crohn's patients who underwent bowel resection during 2002 to 2012. Multivariate regression analysis was performed to investigate outcomes of such patients. We sampled a total of 443,950 patients admitted with the diagnosis of Crohn's disease. Of these, 20.5 per cent had bowel resection. Among patients who had bowel resection, 51 per cent had small bowel Crohn's disease, 19.4 per cent had large bowel Crohn's disease, and 29.6 per cent had both large and small bowel Crohn's disease. Patients with large bowel disease had higher mortality risk compared with small bowel disease [1.8% vs 1%, adjusted odds ratio (AOR): 2.42, P < 0.01]. Risks of postoperative renal failure (AOR: 1.56, P < 0.01) and respiratory failure (AOR: 1.77, P < 0.01) were higher in colonic disease compared with small bowel disease but postoperative enteric fistula was significantly higher in patients with small bowel Crohn's disease (AOR: 1.90, P < 0.01). Of the patients admitted with the diagnosis of Crohn's disease, 20.5 per cent underwent bowel resection during 2002 to 2012. Although colonic disease has a higher mortality risk, small bowel disease has a higher risk of postoperative fistula.


Gut ◽  
1973 ◽  
Vol 14 (4) ◽  
pp. 263-269 ◽  
Author(s):  
J. K. Ritchie ◽  
H. E. Lockhart-Mummery

2016 ◽  
Vol 22 (40) ◽  
pp. 8892 ◽  
Author(s):  
James WT Toh ◽  
Peter Stewart ◽  
Matthew JFX Rickard ◽  
Rupert Leong ◽  
Nelson Wang ◽  
...  

The Lancet ◽  
1990 ◽  
Vol 336 (8711) ◽  
pp. 357-359 ◽  
Author(s):  
A. Ekbom ◽  
H-O Adami ◽  
C. Helmick ◽  
M. Zack

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