scholarly journals Radio-Guided Surgery and Intraoperative iPTH Determination in the Treatment of Primary Hyperparathyroidism

10.5772/29881 ◽  
2012 ◽  
Author(s):  
Paloma Garcia-Talavera ◽  
Jose Ramon

2010 ◽  
Vol 71 (6) ◽  
pp. 511-518 ◽  
Author(s):  
D. Rubello ◽  
N. Kapse ◽  
G. Grassetto ◽  
A. Massaro ◽  
A. Al-Nahhas


2007 ◽  
Vol 14 (12) ◽  
pp. 3401-3402 ◽  
Author(s):  
Brian R. Untch ◽  
Michael E. Barfield ◽  
Joe Bason ◽  
John A. Olson


2017 ◽  
Vol 45 (4) ◽  
pp. 658-666 ◽  
Author(s):  
Elske Quak ◽  
David Blanchard ◽  
Benjamin Houdu ◽  
Yannick Le Roux ◽  
Renaud Ciappuccini ◽  
...  


2014 ◽  
Vol 61 (3) ◽  
pp. 73-76
Author(s):  
Z. Loncar ◽  
K. Tausanovic ◽  
N. Kozarevic ◽  
V. Zivaljevic ◽  
B. Oluic ◽  
...  

Radio-guided surgery offers several advantages in treatment of primary hyperparathyroidism. It is considered less helpful in renal hyperparathyroidism, but it could be of great advantage in the treatment of persistent or recurrent secondary hyperparathyroidism. One of the surgical options for symptomatic renal hyperparathyroidism is total parathyroidectomy with autotransplantation of hyperplastic parathyroid tissue in forearm muscles or sternocleidomastoid muscle. Recurrence can occur and is most likely caused by graft hyperplasia. In this report we present the case of 54-year-old woman with recurrent renal hyperparathyroidism caused by hyperplasia of the graft in sternocleidomastoid muscle. Unfortunately no sutures or clips were placed at initial surgery to identify the location of the parathyroid tissue. The preoperative assessment consisting of 99mTc-sestamibi scintigraphy identified a parathyroid tissue in the in the middle third of sternocleidomastoid muscle. The patient underwent a radio-guided neck re-exploration that allowed a rapid localization and excision of the hyperplastic graft.



2003 ◽  
pp. 7-15 ◽  
Author(s):  
D Rubello ◽  
A Piotto ◽  
D Casara ◽  
PC Muzzio ◽  
B Shapiro ◽  
...  

OBJECTIVE: In the last decade, surgery of primary hyperparathyroidism (HPT) due to a solitary adenoma has moved on from the traditional wide bilateral neck exploration (BNE) to more limited approaches such as unilateral neck exploration and minimally invasive parathyroidectomy. DESIGN: To define the role of intraoperative gamma probe and injection of a low (99m)Tc-MIBI dose in performing minimally invasive radio-guided surgery (MIRS) in HPT patients with a solitary parathyroid adenoma. METHODS: From September 1999 to July 2002, 214 patients with primary HPT entered the study. All patients were preoperatively investigated by a (99m)Tc-pertechnetate/MIBI subtraction scan and high-resolution neck ultrasound. The intraoperative technique we developed differs from other previously described techniques being based on the injection of a low (37 MBq) MIBI dose in the operating theatre a few minutes before the beginning of intervention. RESULTS: On the basis of scan/ultrasound findings 147 patients were selected for a MIRS and 144 of them (98%) were successfully treated by this approach: a solitary parathyroid adenoma was removed through a small 2-2.5 cm skin incision with a mean operative time of 35 min, and a mean hospital stay of 1.2 days. In the other 67 patients with scan/ultrasound evidence of concomitant nodular goiter (n=45) or multi-gland disease (n=13) or with a negative scan (n=9), the gamma probe was utilized during a traditional BNE. A low 37 MBq MIBI dose proved to be sufficient to perform a MIRS; moreover it delivered to the patient and surgeon a low, negligible, radiation exposure dose. CONCLUSIONS: The combination of a (99m)Tc-pertechnetate/MIBI subtraction scan and neck ultrasound appears to be an accurate imaging protocol in selecting primary HPT patients as candidates for a MIRS. A MIBI dose as low as 37 MBq injected in the operating theatre just before the start of surgery appears to be adequate to perform radio-guided surgery.



2006 ◽  
Vol 175 (4S) ◽  
pp. 395-395
Author(s):  
Nancy J. Tresser ◽  
Elena V. Zagaynova ◽  
Olga S. Streltsova ◽  
Natalia D. Gladkova ◽  
Vladislav A. Kamensky ◽  
...  


Ob Gyn News ◽  
2008 ◽  
Vol 43 (3) ◽  
pp. 21
Author(s):  
Miriam E. Tucker
Keyword(s):  


Sign in / Sign up

Export Citation Format

Share Document