scholarly journals Inferior Parathyroid Gland Preservation In Situ during Central Neck Dissection for Thyroid Papillary Carcinoma

2019 ◽  
Author(s):  
Lei Xie ◽  
Jianbiao Wang ◽  
Liang Zhou
Keyword(s):  
Neck Dissection ◽  
Papillary Carcinoma ◽  
Parathyroid Gland ◽  
Central Neck Dissection ◽  
Thyroid Papillary Carcinoma ◽  
Central Neck ◽  
Thyroid Papillary ◽  
Inferior Parathyroid Gland

scholarly journals Effect of autotransplantation of a parathyroid gland on hypoparathyroidism after total thyroidectomy

2018 ◽  
Vol 7 (2) ◽  
pp. 286-294 ◽  
Author(s):  
Anping Su ◽  
Yanping Gong ◽  
Wenshuang Wu ◽  
Rixiang Gong ◽  
Zhihui Li ◽  
...  
Keyword(s):  
Total Thyroidectomy ◽  
Neck Dissection ◽  
Parathyroid Gland ◽  
Central Neck Dissection ◽  
Parathyroid Glands ◽  
Central Neck ◽  
Permanent Hypoparathyroidism ◽  
Papillary Thyroid ◽  
Transient Hypoparathyroidism

Background The effect of parathyroid autotransplantation on hypoparathyroidism is not fully understood. The purpose of the study was to determine the effect of autotransplantation of a parathyroid gland on the incidence of hypoparathyroidism and recovery of parathyroid function at 6 months after total thyroidectomy with central neck dissection for papillary thyroid carcinoma. Methods All patients with autotransplantation of a parathyroid gland (no inadvertent parathyroidectomy) (group A), in situ preservation of all parathyroid glands (no autotransplantation and inadvertent parathyroidectomy) (group B) or inadvertent removal of a parathyroid gland (no autotransplantation) (group C) who underwent first-time total thyroidectomy with central neck dissection for papillary thyroid carcinoma between January 2013 and June 2016 were included retrospectively. Results Of the 702 patients, 383, 297 and 22 were respectively included in the groups A, B and C. The overall rates of transient and permanent hypoparathyroidism were 37.6% and 1.0%. The incidence of transient hypoparathyroidism was 43.9, 29.0 and 45.5% (A vs B, P = 0.000; A vs C, P = 1.000), and the incidence of permanent hypoparathyroidism was 1.0, 0.7 and 4.5% (P > 0.05). The recovery rates of serum parathyroid hormone levels were 71.4, 72.2 and 66.0% at 6-month follow-up (P > 0.05). Conclusion Autotransplantation of a parathyroid gland does not affect the incidence of permanent hypoparathyroidism, but increases the risk of transient hypoparathyroidism when the rest of parathyroid glands are preserved in situ. At least 2 parathyroid glands should be preserved during total thyroidectomy with central neck dissection to prevent permanent hypoparathyroidism.

28. Does variation in central neck dissection and radioactive iodine performance influence the outcome of papillary carcinoma? Comparison of two European experienced centres.

2015 ◽  
Vol 41 (10) ◽  
pp. S87-S88
Author(s):  
Leyre Lorente-Poch ◽  
Mahmud Saedon ◽  
Ioannis Christakis ◽  
German Mateu ◽  
Tarek Ezzat Abdel-Aziz ◽  
...  
Keyword(s):  
Neck Dissection ◽  
Papillary Carcinoma ◽  
Radioactive Iodine ◽  
Central Neck Dissection ◽  
Central Neck

scholarly journals Immunohistochemical and In Situ Hybridization Analyses of Midkine Expression in Thyroid Papillary Carcinoma

2000 ◽  
Vol 13 (10) ◽  
pp. 1060-1065 ◽  
Author(s):  
Masako Kato ◽  
Hiroyuki Maeta ◽  
Shinsuke Kato ◽  
Takao Shinozawa ◽  
Tadashi Terada
Keyword(s):  
In Situ Hybridization ◽  
Papillary Carcinoma ◽  
Thyroid Papillary Carcinoma ◽  
Thyroid Papillary

scholarly journals Application of a cervical low incision in the functional neck dissection of thyroid papillary carcinoma

2016 ◽  
Vol 4 (4) ◽  
pp. 477-482
Author(s):  
JIAJIE XU ◽  
CHAO CHEN ◽  
CHUANMING ZHENG ◽  
KEJING WANG ◽  
JINBIAO SHANG ◽  
...  
Keyword(s):  
Neck Dissection ◽  
Papillary Carcinoma ◽  
Thyroid Papillary Carcinoma ◽  
Thyroid Papillary ◽  
Functional Neck Dissection

scholarly journals Toxic Thyroid Nodule: To FNA or Not?

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A903-A903
Author(s):  
Siva Kumar Kasina ◽  
Erin E Hayward ◽  
Geeta Lal ◽  
Marcelo Correia
Keyword(s):  
Lymph Nodes ◽  
Thyroid Nodule ◽  
Total Thyroidectomy ◽  
Neck Dissection ◽  
Papillary Carcinoma ◽  
Central Neck Dissection ◽  
Graves Disease ◽  
Central Neck ◽  
Thyroid Lobe ◽  
Left Thyroid Lobe

Abstract Background: ATA guidelines recommend evaluation of hyperthyroidism with radioiodine scan and consideration of FNA for non-toxic nodules with suspicious sonographic features. However, there is no standard evidence-based approach to performing ultrasound in patients with toxic nodules. Recent studies have shown increased rates of thyroid cancer in patients with hyperthyroidism and has been shown to demonstrate aggressive histologic features. Clinical Case: A 41-year-old female presented to primary care provider for annual physical exam, found to have intermittent bigeminy and enlarged thyroid on exam. EKG notable for multiple premature ventricular complexes. Evaluation revealed suppressed TSH <0.01 µIU/mL (0.27-4.20), normal free T4 1.27 ng/dL (0.80-1.80), slightly elevated free T3 4.84 pg/mL (2.57-4.43) and elevated TSI 238% (<122). Methimazole was started for treatment of hyperthyroidism. Thyroid sonogram was ordered for abnormal exam, that showed 2.7 cm TIRADS 4 left thyroid nodule with microcalcifications. I-131 uptake values were 20% and 49% at 4-hours and 24-hours, respectively. Technetium-99M scan showed toxic autonomous nodule in the left thyroid lobe corresponding to the one seen on sonogram. The remainder of the thyroid gland showed heterogeneously suppressed uptake. FNA of the thyroid nodule was done due to the presence of microcalcifications and the cytopathology was suspicious for papillary carcinoma. She underwent total thyroidectomy with central neck dissection involving pre-tracheal and paratracheal lymph nodes (level VI). Pathology showed 1.4 cm papillary carcinoma with lymphovascular space invasion and multifocal papillary microcarcinomas in the left thyroid lobe, 0.2 cm papillary microcarcinoma in right thyroid lobe, metastatic papillary carcinoma in 2 out of 5 lymph nodes, largest metastatic deposit 0.1 cm in the largest dimension with no extra nodal extension. There was also follicular hyperplasia noted consistent with Graves’ disease. Post-operatively, she had thyrogen-stimulated adjuvant RAI treatment, dose 107.4 mCi. Post therapy scan did not show evidence of distant metastases. Conclusion: This case demonstrates the identification of a metastatic papillary thyroid carcinoma based on suspicious ultrasound features requiring total thyroidectomy, central neck dissection and adjunct radioactive iodine in a patient with hyperthyroidism from co-existent toxic thyroid nodule and Graves’ disease.

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