scholarly journals Fiber scaffold bioartificial liver therapy relieves acute liver failure and extrahepatic organ injury in pigs

Theranostics ◽  
2021 ◽  
Vol 11 (16) ◽  
pp. 7620-7639
Author(s):  
Jun Weng ◽  
Xu Han ◽  
Fanhong Zeng ◽  
Yue Zhang ◽  
Lei Feng ◽  
...  
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Bioartificial Liver ◽  
Organ Injury

DEMONSTRATION OF THE EFFICIENCY OF A BIOARTIFICIAL LIVER IN A POTENTIALLY REVERSIBLE LARGE ANIMAL MODEL OF ACUTE LIVER FAILURE.

2000 ◽  
Vol 69 (Supplement) ◽  
pp. S405
Author(s):  
I. Fourneau ◽  
S. H. Yap ◽  
T. Roskams ◽  
L. Flendrig ◽  
R. Chamuleau ◽  
...  
Keyword(s):  
Animal Model ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Bioartificial Liver ◽  
Large Animal Model ◽  
Large Animal

Effects of acute-liver-failure-plasma exposure on hepatic functionality of HepaRG-AMC-Bioartificial Liver

2013 ◽  
Vol 33 (4) ◽  
pp. 516-524 ◽  
Author(s):  
Geert A. A. Nibourg ◽  
Ruurdtje Hoekstra ◽  
Tessa V. van der Hoeven ◽  
Mariëtte T. Ackermans ◽  
Theodorus B. M. Hakvoort ◽  
...  
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Bioartificial Liver ◽  
Plasma Exposure

Issues in Bioartificial Liver Support Therapy for Acute Liver Failure

2010 ◽  
pp. 201-219 ◽  
Author(s):  
John F. Patzer ◽  
Jörg C. Gerlach
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Bioartificial Liver ◽  
Liver Support ◽  
Bioartificial Liver Support

Acute Liver Failure and Bioartificial Liver Support

2019 ◽  
pp. 1508-1516
Author(s):  
Harvey S. Chen ◽  
Jian Yang ◽  
Scott L. Nyberg
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Bioartificial Liver ◽  
Liver Support ◽  
Bioartificial Liver Support

Assessment of Bioartificial Liver Support in Acute Liver Failure

1996 ◽  
Vol 19 (1) ◽  
pp. 3-6 ◽  
Author(s):  
R.D. Hughes ◽  
R. Williams
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Bioartificial Liver ◽  
Liver Support ◽  
Bioartificial Liver Support

NEUROLOGICAL IMPROVEMENT DURING BIOARTIFICIAL LIVER SESSIONS IN PATIENTS WITH ACUTE LIVER FAILURE AWAITING TRANSPLANTATION1

2002 ◽  
Vol 73 (2) ◽  
pp. 257-264 ◽  
Author(s):  
Didier Samuel ◽  
Philippe Ichai ◽  
Cyrille Feray ◽  
Faouzi Saliba ◽  
Daniel Azoulay ◽  
...  
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Bioartificial Liver ◽  
Neurological Improvement

Chemokines and mitochondrial products activate neutrophils to amplify organ injury during mouse acute liver failure

Hepatology ◽  
2012 ◽  
Vol 56 (5) ◽  
pp. 1971-1982 ◽  
Author(s):  
Pedro E. Marques ◽  
Sylvia S. Amaral ◽  
Daniele A. Pires ◽  
Laura L. Nogueira ◽  
Frederico M. Soriani ◽  
...  
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Organ Injury

scholarly journals Experimental research on TECA-I bioartificial liver support system to treat canines with acute liver failure

2001 ◽  
Vol 7 (5) ◽  
pp. 706 ◽  
Author(s):  
Xiao-Ping Chen ◽  
Yi-Long Xue ◽  
Xin-Jian Li ◽  
Zuo-Yun Zhang ◽  
Yan-Ling Li ◽  
...  
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Experimental Research ◽  
Support System ◽  
Bioartificial Liver ◽  
Liver Support ◽  
Liver Support System ◽  
Bioartificial Liver Support

scholarly journals The study of albumin dialysis efficiency in acute liver failure using the «Bioartificial liver» device

2015 ◽  
Vol 96 (5) ◽  
pp. 768-771
Author(s):  
E E Polevshchikova
Keyword(s):  
Liver Failure ◽  
Acute Liver Failure ◽  
Biochemical Markers ◽  
Clinical Signs ◽  
Human Albumin ◽  
Bioartificial Liver ◽  
Experimental Sample ◽  
Albumin Solution ◽  
Albumin Dialysis ◽  
Bioartificial Liver Device

Aim. Clinical testing of albumin dialysis method in patients with acute liver failure of different etiologies on the experimental sample of the «bioartificial liver» device. Methods. Clinical assessment of treatment using the «bioartificial liver» device was conducted on 20 patients aged 22-68 years old who had acute liver failure of different etiology. The «bioartificial liver» device consisted of a perfusion unit, the dialyzer, dialysis circuit with albumin solution and carbon haemosorbent mode. A 10% donor human albumin solution was used as the dialysis fluid in recirculation mode. For restoration of the accepting ability albumin was exposed to perfusion through the carbonic hemosorbent. Duration of the treatment was 3 hours, control of liver damage biochemical markers was performed before and after the session. Results. There was a statistically significant reduction in biochemical markers of cytolysis and cholestasis: transaminases, alkaline phosphatase and bilirubin levels. We also observed a statistically significant reduction of ammonia level, which is one of the main clinical and laboratory signs characterizing the severity of encephalopathy. Improvement of liver synthetic function reflected a statistically significant increase in glucose level. Clinical stabilization as well as reduction of encephalopathy clinical signs were observed after the procedure. No side effects were notices. Conclusion. Implementation of albumin dialysis in patients with acute liver failure using the «bioartificial liver» device was accompanied by an improvement of their functional state. This gives reason to use this method for the treatment of acute liver failure in intensive care units.

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