scholarly journals Enantiomer Separation of Chiral Amino Alcohols as 9-anthraldimine Derivatives on Coated and Covalently Bonded Chiral Stationary Phases Based on Polysaccharide Derivatives by High Performance Liquid Chromatography

KSBB Journal ◽  
2011 ◽  
Vol 26 (4) ◽  
pp. 323-327 ◽  
Author(s):  
Wen Jun Xu ◽  
Jing Yu Jin ◽  
Won-Jae Lee
2007 ◽  
Vol 79 (9) ◽  
pp. 1561-1573 ◽  
Author(s):  
Xiaoming Chen ◽  
Chiyo Yamamoto ◽  
Yoshio Okamoto

The chromatographic separation of enantiomers using chiral stationary phases (CSPs) has significantly advanced. The esters and carbamates of polysaccharides coated on silica gel have been extensively studied and widely used as CSPs for high-performance liquid chromatography (HPLC). In order to overcome the strict solvent limitation on these coated CSPs, the preparation of a new generation of CSPs consisting of immobilized polysaccharide derivatives has become increasingly important. The universal solvent compatibility of the new CSPs provides flexibility in both analytical and preparative chromatographies.


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