reformatsky reaction
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Reformatsky reaction as a key step in the synthesis of natural products: A review

2021 ◽  
pp. 1-29
Author(s):  
Sadaf Saeed ◽  
Ameer Fawad Zahoor ◽  
Sajjad Ahmad ◽  
Rabia Akhtar ◽  
Sana Sikandar
Keyword(s):  
Natural Products ◽  
Reformatsky Reaction

scholarly journals Difluoroalkylation of tertiary amides and lactams by an iridium-catalyzed reductive Reformatsky reaction

2021 ◽  
Author(s):  
Phillip Biallas ◽  
Ken Yamazaki ◽  
Darren J. Dixon
Keyword(s):  
Late Stage ◽  
Reformatsky Reaction ◽  
Reductive Alkylation ◽  
Tertiary Amides

The synthesis of medicinally relevant α-difluoroalkylated amines by an iridium-catalyzed reductive alkylation of tertiary amides and lactams with difluoro-Reformatsky reagents, is described. This report features the introduction of various geminal difluoro-acetates and -acetamides as well as late stage derivatization of APIs, gram scale synthesis and downstream functionalizations.

Reformatsky Reaction

2021 ◽  
pp. 468-470
Author(s):  
Jie Jack Li
Keyword(s):  
Reformatsky Reaction

scholarly journals Manganese-Mediated Reformatsky Reaction: Highly Divergent Synthesis ofβ-Hydroxyalkanoates

2021 ◽  
Vol 41 (1) ◽  
pp. 341
Author(s):  
Yanping Xia ◽  
Lu Ouyang ◽  
Jianhua Liao ◽  
Yifei Wei ◽  
Renshi Luo
Keyword(s):  
Reformatsky Reaction

Reformatsky Reaction of 1-Aryl-3-(2-hydroxyphenyl)prop-2-en-1-ones with Methyl 1-Bromocyclohexanecarboxylate

2020 ◽  
Vol 56 (12) ◽  
pp. 2074-2078
Author(s):  
E. A. Nikiforova ◽  
D. V. Baibarodskikh ◽  
N. F. Kirillov ◽  
M. V. Dmitriev ◽  
D. P. Zverev
Keyword(s):  
Reformatsky Reaction

Enantioselective Reformatsky Reaction of Ketones Catalyzed by Chiral Indolinylmethanol

2020 ◽  
Vol 2020 (30) ◽  
pp. 4805-4811
Author(s):  
Renshi Luo ◽  
Miao-Miao Chen ◽  
Lu Ouyang ◽  
Albert S. C. Chan ◽  
Gui Lu
Keyword(s):  
Reformatsky Reaction

scholarly journals Highly Catalytic Enantioselective Reformatsky Reaction with Aldehydes and Ketones Using an Available Prolinol Ligand

ACS Omega ◽  
2020 ◽  
Vol 5 (27) ◽  
pp. 16967-16975
Author(s):  
Lu Ouyang ◽  
YanPing Xia ◽  
YiFei Wei ◽  
Jianhua Liao ◽  
Renshi Luo
Keyword(s):  
Reformatsky Reaction ◽  
Aldehydes And Ketones

Reformatsky Reaction of Methyl 1-Bromocyclohexanecarboxylate with N,N′-(1,4-Phenylene)bis(1-arylmethanimines)

2020 ◽  
Vol 56 (6) ◽  
pp. 1029-1033
Author(s):  
E. A. Nikiforova ◽  
D. V. Baibarodskikh ◽  
N. F. Kirillov ◽  
L. A. Glavatskikh
Keyword(s):  
Reformatsky Reaction
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