physiologically based pharmacokinetic model Recently Published Documents

Development of physiologically based pharmacokinetic model using artificial intelligence based approaches for pravastatin during pregnancy

American Journal of Obstetrics and Gynecology ◽

10.1016/j.ajog.2021.11.1142 ◽

2022 ◽

Vol 226 (1) ◽

pp. S692-S693

Author(s):

Ananth Kumar Kammala ◽

Lauren Richardson ◽

RamKumar Menon

Keyword(s):

Artificial Intelligence ◽

Pharmacokinetic Model ◽

Assessment of drug–drug interaction and optimization in capecitabine and irinotecan combination regimen using a physiologically based pharmacokinetic model

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2021.12.021 ◽

2021 ◽

Author(s):

Shuhei Sakai ◽

Shinji Kobuchi ◽

Yukako Ito ◽

Toshiyuki Sakaeda

Keyword(s):

Drug Interaction ◽

Pharmacokinetic Model ◽

Combination Regimen ◽

Physiologically Based ◽

Drug Drug Interaction

Characterization of Preclinical Pharmacokinetic Properties and Prediction of Human PK Using a Physiologically Based Pharmacokinetic Model for a Novel Anti-Arrhythmic Agent Sulcardine Sulfate

Pharmaceutical Research ◽

10.1007/s11095-021-03128-3 ◽

2021 ◽

Author(s):

Chang Ren ◽

Yao Wang ◽

Mei Zhang ◽

Dexuan Kong ◽

Chen Ning ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Pharmacokinetic Properties ◽

Bayesian Refinement of the Permeability-Limited Physiologically Based Pharmacokinetic Model for Perfluorooctanoic Acid in Male Rats

Chemical Research in Toxicology ◽

10.1021/acs.chemrestox.1c00193 ◽

2021 ◽

Author(s):

Weixiao Cheng ◽

Carla A. Ng

Keyword(s):

Pharmacokinetic Model ◽

Perfluorooctanoic Acid ◽

Male Rats ◽

Physiologically based pharmacokinetic model revealed the distinct bio-transportation and turnover of arsenobetaine and arsenate in marine fish

Aquatic Toxicology ◽

10.1016/j.aquatox.2021.105991 ◽

2021 ◽

pp. 105991

Author(s):

Haiyan Xiong ◽

Qiao-Guo Tan ◽

Jichao Zhang ◽

Wen-Xiong Wang ◽

Xiangzhou Yuan ◽

...

Keyword(s):

Marine Fish ◽

Pharmacokinetic Model ◽

Extrapolation of physiologically based pharmacokinetic model for tacrolimus from renal to liver transplant patients

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2021.100423 ◽

2021 ◽

pp. 100423

Author(s):

Kotaro Itohara ◽

Ikuko Yano ◽

Shunsaku Nakagawa ◽

Atsushi Yonezawa ◽

Tomohiro Omura ◽

...

Keyword(s):

Liver Transplant ◽

Pharmacokinetic Model ◽

Transplant Patients ◽

Hepatic Impairment Physiologically Based Pharmacokinetic Model Development: Current Challenges

Current Pharmacology Reports ◽

10.1007/s40495-021-00266-5 ◽

2021 ◽

Author(s):

Agnes Nuo Han ◽

Beatrice Rae Han ◽

Tao Zhang ◽

Tycho Heimbach

Keyword(s):

Hepatic Impairment ◽

Pharmacokinetic Model ◽

Model Development ◽

Physiologically‐based pharmacokinetic model predictions of inter‐ethnic differences in imatinib pharmacokinetics and dosing regimens

British Journal of Clinical Pharmacology ◽

10.1111/bcp.15084 ◽

2021 ◽

Author(s):

Jeffry Adiwidjaja ◽

Annette S. Gross ◽

Alan V. Boddy ◽

Andrew J. McLachlan

Keyword(s):

Ethnic Differences ◽

Pharmacokinetic Model ◽

Model Predictions ◽

Physiologically Based ◽

Dosing Regimens

Pharmacokinetics and safety of rilpivirine in healthy Japanese subjects and exploration of ethnic sensitivity of rilpivirine pharmacokinetics with physiologically based pharmacokinetic model approach

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2021.100422 ◽

2021 ◽

pp. 100422

Author(s):

Kentaro Ohta ◽

Nobuko Matsushima ◽

Hiromi Tanii ◽

Herta Crauwels ◽

Toshiyuki Kudo ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Physiologically Based ◽

Ethnic Sensitivity ◽

Japanese Subjects ◽

Model Approach