physiologically based pharmacokinetic models Recently Published Documents

Development of physiologically‐based pharmacokinetic models for standard of care and newer tuberculosis drugs

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12707 ◽

2021 ◽

Author(s):

Helen Humphries ◽

Lisa Almond ◽

Alexander Berg ◽

Iain Gardner ◽

Oliver Hatley ◽

...

Keyword(s):

Standard Of Care ◽

Pharmacokinetic Models ◽

An Updated In Silico Prediction Method for Volumes of Systemic Circulation of 323 Disparate Chemicals for Use in Physiologically Based Pharmacokinetic Models to Estimate Plasma and Tissue Concentrations after Oral Doses in Rats

Chemical Research in Toxicology ◽

10.1021/acs.chemrestox.1c00249 ◽

2021 ◽

Author(s):

Yusuke Kamiya ◽

Kentaro Handa ◽

Tomonori Miura ◽

Junya Ohori ◽

Makiko Shimizu ◽

...

Keyword(s):

In Silico ◽

Prediction Method ◽

Systemic Circulation ◽

Pharmacokinetic Models ◽

In Silico Prediction ◽

Tissue Concentrations ◽

Physiologically Based ◽

Oral Doses

APPLICATIONS OF PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS INTEGRATED WITH DRUG EFFECT MODELS (PBPK/PD)

10.1002/9781119497813.ch13 ◽

2021 ◽

pp. 353-374

Keyword(s):

Drug Effect ◽

Pharmacokinetic Models ◽

Physiologically Based Pharmacokinetic Models Are Effective Support for Pediatric Drug Development

AAPS PharmSciTech ◽

10.1208/s12249-021-02076-w ◽

2021 ◽

Vol 22 (6) ◽

Author(s):

Kefei Wang ◽

Kun Jiang ◽

Xiaoyi Wei ◽

Yulan Li ◽

Tiejie Wang ◽

...

Keyword(s):

Drug Development ◽

Pharmacokinetic Models ◽

Pediatric Drug ◽

Pediatric Drug Development ◽

Combination of a biopharmaceutic classification system and physiologically based pharmacokinetic models to predict absorption properties of baicalein in vitro and in vivo

Journal of Traditional Chinese Medical Sciences ◽

10.1016/j.jtcms.2021.07.006 ◽

2021 ◽

Author(s):

Yang Liu ◽

Jing Sun ◽

Lin Ying Zhong ◽

Yu Li ◽

A Na Er ◽

...

Keyword(s):

Classification System ◽

Pharmacokinetic Models ◽

Absorption Properties ◽

Biopharmaceutic Classification System

Physiologically Based ◽

Evaluation of Physiologically Based Pharmacokinetic Models to Predict the Absorption of BCS Class I Drugs in Different Pediatric Age Groups

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1845 ◽

2021 ◽

Vol 61 (S1) ◽

Author(s):

Xiaomei I. Liu ◽

John N. den Anker ◽

Gilbert J. Burckart ◽

André Dallmann

Keyword(s):

Age Groups ◽

Class I ◽

Pediatric Age ◽

Pharmacokinetic Models ◽

Application of physiologically based pharmacokinetic models to promote the development of veterinary drugs with high efficacy and safety

Journal of Veterinary Pharmacology and Therapeutics ◽

10.1111/jvp.12976 ◽

2021 ◽

Author(s):

Kaixiang Zhou ◽

Kun Mi ◽

Wenjin Ma ◽

Xiangyue Xu ◽

Meixia Huo ◽

...

Keyword(s):

Veterinary Drugs ◽

Pharmacokinetic Models ◽

Efficacy And Safety ◽

High Efficacy ◽

Hepatotoxicological potential of p-toluic acid in humanized-liver mice investigated using simplified physiologically based pharmacokinetic models

Xenobiotica ◽

10.1080/00498254.2021.1908643 ◽

2021 ◽

pp. 1-25

Author(s):

Tomonori Miura ◽

Yusuke Kamiya ◽

Shotaro Uehara ◽

Norie Murayama ◽

Makiko Shimizu ◽

...

Keyword(s):

Pharmacokinetic Models ◽

Fetal Physiologically Based Pharmacokinetic Models: Systems Information on Fetal Cardiac Output and Its Distribution to Different Organs during Development

Clinical Pharmacokinetics ◽

10.1007/s40262-020-00973-0 ◽

2021 ◽

Author(s):

Khaled Abduljalil ◽

Xian Pan ◽

Ruth Clayton ◽

Trevor N. Johnson ◽

Masoud Jamei

Keyword(s):

Cardiac Output ◽

Pharmacokinetic Models ◽