AbstractThis paper considers the initial-boundary value problem of the one-dimensional full compressible nematic liquid crystal flow problem. The initial density is allowed to touch vacuum, and the viscous and heat conductivity coefficients are kept to be positive constants. Global existence of strong solutions is established for any $H^{2}$
H
2
initial data in the Lagrangian flow map coordinate, which holds for both vacuum and non-vacuum case. The key difficulty is caused by the lack of the positive lower bound of the density. To overcome such difficulty, it is observed that the ratio of $\frac{\rho _{0(y)}}{\rho (t,y)}$
ρ
0
(
y
)
ρ
(
t
,
y
)
is proportional to the time integral of the upper bound of temperature and vector director field, along the trajectory. Density weighted Sobolev type inequalities are constructed for both temperature and director field in terms of $\frac{\rho _{0(y)}}{\rho (t,y)}$
ρ
0
(
y
)
ρ
(
t
,
y
)
and small dependence on their dissipation estimates. Besides this, to deal with cross terms arising due to liquid crystal flow, higher order priori estimates are established by using effective viscous flux.