Let F be the free group of rank 2 with basis {x, y}, and G a metabelian product of some non-trivial abelian groups. If not all the factors of G are torsion groups, it is proved that the verbal subgroup of G in F equals F″. Moreover, all the 2-symmetric words of G are determined by using left Fox derivatives. In addition, we provide an example to illustrate that if all the factors of G are torsion groups, the above results need not be true.