Spiro-indolizidine scaffolds are attractive structural motifs in natural alkaloids and pharmaceuticals. Herein, we descirbed a highly stereoselective dearomatizative [3+2] cycloaddition between cyclic pyridinium ylides and nitroolefins. A novel type of...
Indolizines and pyrazolo[1,5-a]pyridines were prepared via 3+2]-cycloaddition of pyridinium ylides to 1-chloro-2-nitrostyrenes. The synthesized molecules were evaluated for antiproliferative activities against a BE(2)-C neuroblastoma cell line with several compounds decreasing...
Two new kinds of cyclic pyridinium ylides have been firstly designed and used in reactions with in situ generated azoalkenes to access spirocyclic compounds via a [4 + 1] annulation process.
Correction to “Three-Component Condensation of Pyridinium Ylides, β-Ketonitriles, and Aldehydes with Divergent Regioselectivity: Synthesis of 4,5-Dihydrofuran-3- and 2H-Pyran-5-carbonitriles”
