In negative shear tokamak discharges, an excessively large Shafranov shift (Δ') destabilizes the magnetohydrodynamic ballooning mode. A kinetic model, local to a flux surface and which employs the ballooning-mode representation of the gyrokinetic equations, also predicts the existence of the instability as does two-fluid theory.PACS Nos.: 52.35.Fp, 52.35.Kt, 52.55.Fa