Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases

Application of Minimal Anticipated Biological Effect Level (MABEL) in Human Starting Dose Selection for Immunomodulatory Protein Therapeutics - Principles and Case Studies

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases ◽

10.1002/9781119289234.ch4 ◽

2019 ◽

pp. 65-91

Author(s):

Haiqing Wang ◽

Zheng Yang ◽

Rong Shi

Keyword(s):

Case Studies ◽

Biological Effect ◽

Protein Therapeutics ◽

Dose Selection ◽

Starting Dose ◽

Effect Level ◽

Selection For ◽

Immunomodulatory Protein

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Tutorial: Numerical (NONMEM) Implementation of the Target-Mediated Drug Disposition Model

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases ◽

10.1002/9781119289234.ch8 ◽

2019 ◽

pp. 173-186

Author(s):

Leonid Gibiansky ◽

Ekaterina Gibiansky

Keyword(s):

Drug Disposition ◽

Target Mediated Drug Disposition ◽

Disposition Model

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Case Examples of Using Quantitative Pharmacology in Developing Therapeutic Proteins for Plaque Psoriasis - Guselkumab

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases ◽

10.1002/9781119289234.ch15 ◽

2019 ◽

pp. 337-361

Author(s):

Zhenling Yao ◽

Yaowei Zhu ◽

Chuanpu Hu ◽

Yang Chen ◽

Shu Li ◽

...

Keyword(s):

Plaque Psoriasis ◽

Therapeutic Proteins ◽

Case Examples ◽

Quantitative Pharmacology

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Supplemental Images

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases ◽

10.1002/9781119289234.ins ◽

2019 ◽

pp. 1-16

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Pharmacokinetics-Based Dosing for Therapeutic Monoclonal Antibodies in Inflammatory Bowel Disease

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases ◽

10.1002/9781119289234.ch11 ◽

2019 ◽

pp. 243-253

Author(s):

Niels Vande Casteele ◽

William J. Sandborn

Keyword(s):

Inflammatory Bowel Disease ◽

Monoclonal Antibodies ◽

Bowel Disease ◽

Inflammatory Bowel ◽

Therapeutic Monoclonal Antibodies

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Index

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases ◽

10.1002/9781119289234.index ◽

2019 ◽

pp. 437-465

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Translational Considerations in Developing Bispecific Antibodies: What Can We Learn from Quantitative Pharmacology?

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases ◽

10.1002/9781119289234.ch9 ◽

2019 ◽

pp. 187-208

Author(s):

Pradeep B. Lukka ◽

Santosh Wagh ◽

Bernd Meibohm

Keyword(s):

Bispecific Antibodies ◽

Quantitative Pharmacology

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Application of Pharmacometrics and Systems Pharmacology to Current and Emerging Biologics in Inflammatory Bowel Diseases

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases ◽

10.1002/9781119289234.ch10 ◽

2019 ◽

pp. 209-242

Author(s):

Sihem Ait-Oudhia ◽

Yi Ting Kayla Lien ◽

Sumit Basu ◽

Lawrence Lesko ◽

Stephan Schmidt

Keyword(s):

Inflammatory Bowel Diseases ◽

Systems Pharmacology ◽

Bowel Diseases ◽

Inflammatory Bowel

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Pharmacokinetics-Based Dosing Strategies for Therapeutic Proteins in Inflammatory Bowel Disease

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases ◽

10.1002/9781119289234.ch12 ◽

2019 ◽

pp. 255-284

Author(s):

Diane R. Mould ◽

Richard N. Upton ◽

Jessica Wojciechowski

Keyword(s):

Inflammatory Bowel Disease ◽

Bowel Disease ◽

Therapeutic Proteins ◽

Dosing Strategies ◽

Inflammatory Bowel

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Disease Interception in Autoimmune Diseases: From a Conceptual Framework to Practical Implementation

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases ◽

10.1002/9781119289234.ch1 ◽

2019 ◽

pp. 1-23

Author(s):

Anish Suri

Keyword(s):

Autoimmune Diseases ◽

Conceptual Framework ◽

Practical Implementation

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Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases
Latest Publications

TOTAL DOCUMENTS

H-INDEX

Published By John Wiley & Sons, Inc.

Application of Minimal Anticipated Biological Effect Level (MABEL) in Human Starting Dose Selection for Immunomodulatory Protein Therapeutics - Principles and Case Studies

Tutorial: Numerical (NONMEM) Implementation of the Target-Mediated Drug Disposition Model

Case Examples of Using Quantitative Pharmacology in Developing Therapeutic Proteins for Plaque Psoriasis - Guselkumab

Supplemental Images

Pharmacokinetics-Based Dosing for Therapeutic Monoclonal Antibodies in Inflammatory Bowel Disease

Index

Translational Considerations in Developing Bispecific Antibodies: What Can We Learn from Quantitative Pharmacology?

Application of Pharmacometrics and Systems Pharmacology to Current and Emerging Biologics in Inflammatory Bowel Diseases

Pharmacokinetics-Based Dosing Strategies for Therapeutic Proteins in Inflammatory Bowel Disease

Disease Interception in Autoimmune Diseases: From a Conceptual Framework to Practical Implementation

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Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory DiseasesLatest Publications

TOTAL DOCUMENTS

H-INDEX

Published By John Wiley & Sons, Inc.

Application of Minimal Anticipated Biological Effect Level (MABEL) in Human Starting Dose Selection for Immunomodulatory Protein Therapeutics - Principles and Case Studies

Tutorial: Numerical (NONMEM) Implementation of the Target-Mediated Drug Disposition Model

Case Examples of Using Quantitative Pharmacology in Developing Therapeutic Proteins for Plaque Psoriasis - Guselkumab

Supplemental Images

Pharmacokinetics-Based Dosing for Therapeutic Monoclonal Antibodies in Inflammatory Bowel Disease

Index

Translational Considerations in Developing Bispecific Antibodies: What Can We Learn from Quantitative Pharmacology?

Application of Pharmacometrics and Systems Pharmacology to Current and Emerging Biologics in Inflammatory Bowel Diseases

Pharmacokinetics-Based Dosing Strategies for Therapeutic Proteins in Inflammatory Bowel Disease

Disease Interception in Autoimmune Diseases: From a Conceptual Framework to Practical Implementation

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases
Latest Publications