This chapter explores how evangelical internationalism developed into a focused vision for U.S. foreign relations that provided the foundation for political advocacy on a wide range of global issues by the late 1970s and early 1980s. It argues that a powerful evangelical foreign policy emerged in response to growing anxieties about developments in international relations. It also explains how evangelicals drew on their connections with coreligionists abroad and combined their spiritual beliefs with human rights language in order to build support among policymakers for the cause of international religious liberty. The chapter reflects the layered and multimodal nature of evangelical internationalist development and of the foreign policy challenges that evangelical activists confronted. It also reveals how evangelical leaders, missionaries, and interest groups drew on their political power and the international evangelical network to shape international relations and national policies in the United States, the Soviet Union, Guatemala, and South Africa.