Drug Discovery - Epigenetics for Drug Discovery
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Published By Royal Society Of Chemistry

9781849738828
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CHAPTER 12. Safety Considerations for Epigenetic Mechanisms as Drug Targets: Are Existing Toxicology Studies Fit for Purpose?

2015 ◽  
pp. 288-315
Author(s):  
Paul Butler ◽  
Michael Lawton ◽  
Robert E. Chapin ◽  
Brett D. Hollingshead ◽  
Karen Leach ◽  
...  
Keyword(s):  
Drug Targets ◽  
Epigenetic Mechanisms ◽  
Fit For Purpose ◽  
Safety Considerations

CHAPTER 10. Dosing – When Less is More

2015 ◽  
pp. 249-266
Author(s):  
Kurinji Pandiyan ◽  
Peter A. Jones ◽  
Stephen B. Baylin
Keyword(s):  
Less Is More

CHAPTER 5. Targeting Histone Acetylation

2015 ◽  
pp. 96-126
Author(s):  
Daniel Vitt ◽  
Roland Baumgartner ◽  
Hella Kohlhof
Keyword(s):  
Histone Acetylation

Subject Index

2015 ◽  
pp. 316-321

CHAPTER 11. Histone Methyltransferase Activity Assays

2015 ◽  
pp. 267-287 ◽  
Author(s):  
Haiching Ma ◽  
Konrad T. Howitz ◽  
Kurumi Y. Horiuchi ◽  
Yuren Wang
Keyword(s):  
Histone Methyltransferase ◽  
Methyltransferase Activity

CHAPTER 1. Epigenetics – What it is and Why it Matters

2015 ◽  
pp. 1-19
Author(s):  
Karl P. Nightingale

Preface

2015 ◽  
pp. P007-P008

Front Matter

2015 ◽  
pp. P001-P006

CHAPTER 9. Who will Benefit from Epigenetic Drugs?

2015 ◽  
pp. 230-248
Author(s):  
Dominique Verhelle ◽  
David J. Shields
Keyword(s):  
Epigenetic Drugs
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