Methods in Pharmacology and Toxicology - Optimization in Drug Discovery
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Published By Humana Press

9781627037419, 9781627037426

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In Situ Single Pass Perfused Rat Intestinal Model

Methods in Pharmacology and Toxicology - Optimization in Drug Discovery ◽

10.1007/978-1-62703-742-6_5 ◽

2013 ◽

pp. 77-86

Author(s):

Maria Markowska ◽

L. Mark Kao

Keyword(s):

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In Vitro Characterization of Hepatic Transporters OATP1B1 and OATP1B3

Methods in Pharmacology and Toxicology - Optimization in Drug Discovery ◽

10.1007/978-1-62703-742-6_23 ◽

2013 ◽

pp. 405-416

Author(s):

Blair Miezeiewski ◽

Allison McLaughlin

Keyword(s):

In Vitro Characterization ◽

Hepatic Transporters

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Assessment of CYP3A4 Time-Dependent Inhibition in Plated and Suspended Human Hepatocytes

Methods in Pharmacology and Toxicology - Optimization in Drug Discovery ◽

10.1007/978-1-62703-742-6_15 ◽

2013 ◽

pp. 255-268

Author(s):

J. George Zhang ◽

David M. Stresser

Keyword(s):

Human Hepatocytes ◽

Time Dependent ◽

Dependent Inhibition ◽

Time Dependent Inhibition

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In Vitro Trapping and Screening of Reactive Metabolites Using Liquid Chromatography-Mass Spectrometry

Methods in Pharmacology and Toxicology - Optimization in Drug Discovery ◽

10.1007/978-1-62703-742-6_28 ◽

2013 ◽

pp. 477-488 ◽

Author(s):

Zhengyin Yan ◽

Gary W. Caldwell

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Reactive Metabolites ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry

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Screening for P-Glycoprotein (Pgp) Substrates and Inhibitors

Methods in Pharmacology and Toxicology - Optimization in Drug Discovery ◽

10.1007/978-1-62703-742-6_20 ◽

2013 ◽

pp. 337-352

Author(s):

Qing Wang ◽

Tina M. Sauerwald

Keyword(s):

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In Vitro Characterization of Intestinal and Hepatic Transporters: MRP2

Methods in Pharmacology and Toxicology - Optimization in Drug Discovery ◽

10.1007/978-1-62703-742-6_22 ◽

2013 ◽

pp. 369-404

Author(s):

Ravindra Varma Alluri ◽

Peter Ward ◽

Jeevan R. Kunta ◽

Brian C. Ferslew ◽

Dhiren R. Thakker ◽

...

Keyword(s):

In Vitro Characterization ◽

Hepatic Transporters

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Methods for Using the Mouse Lymphoma Assay to Screen for Chemical Mutagenicity and Photo-Mutagenicity

Methods in Pharmacology and Toxicology - Optimization in Drug Discovery ◽

10.1007/978-1-62703-742-6_34 ◽

2013 ◽

pp. 561-592 ◽

Author(s):

Nan Mei ◽

Xiaoqing Guo ◽

Martha M. Moore

Keyword(s):

Mouse Lymphoma Assay ◽

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In Vitro Assessment of the Reactivity of Acyl Glucuronides

Methods in Pharmacology and Toxicology - Optimization in Drug Discovery ◽

10.1007/978-1-62703-742-6_30 ◽

2013 ◽

pp. 505-516

Author(s):

Rongfang Fran Xu ◽

Wing W. Lam ◽

Jie Chen ◽

Michael McMillian ◽

Jose Silva ◽

...

Keyword(s):

Acyl Glucuronides ◽

In Vitro Assessment

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Characterization of Constitutive Androstane Receptor (CAR) Activation

Methods in Pharmacology and Toxicology - Optimization in Drug Discovery ◽

10.1007/978-1-62703-742-6_11 ◽

2013 ◽

pp. 195-205 ◽

Author(s):

Caitlin Lynch ◽

Haishan Li ◽

Hongbing Wang

Keyword(s):

Constitutive Androstane Receptor

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Metabolic Assessment in Alamethicin-Activated Liver Microsomes: Co-activating CYPs and UGTs

Methods in Pharmacology and Toxicology - Optimization in Drug Discovery ◽

10.1007/978-1-62703-742-6_7 ◽

2013 ◽

pp. 101-115 ◽

Author(s):

Gary W. Caldwell ◽

Zhengyin Yan

Keyword(s):

Liver Microsomes

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