Population-Based Study of Sleep-Disordered Breathing as a Risk Factor for Hypertension

1997 ◽  
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Terry Young
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M.W. Gerbase ◽  
J. Dratva ◽  
M. Germond ◽  
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J.L. Pépin ◽  
...  

2001 ◽  
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E. Lindberg ◽  
C. Berne ◽  
C. Janson ◽  
T. Gislason ◽  
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2018 ◽  
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Yen-Ling Shen ◽  
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Hsiao-Chi Chuang ◽  
Hua-Wei Chen ◽  
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2000 ◽  
Vol 162 (6) ◽  
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LAUREL FINN ◽  
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PAUL E. PEPPARD ◽  
M. SAFWAN BADR ◽  
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Nelda M. Garcia ◽  
...  

BackgroundWe sought to investigate the frequency of wake-up stroke (WUS) and its association with sleep-disordered breathing (SDB) in women.MethodsWithin a population-based study, women with acute ischemic stroke were asked about their stroke symptom onset time. SDB screening was performed with the well-validated ApneaLink Plus device; SDB was defined by a respiratory event index ≥10. Logistic regression was used to test the association between SDB presence and severity and WUS unadjusted and adjusted for potential confounders including prestroke depression and sleep duration.ResultsAmong 466 participants, the median age was 67.0 years (interquartile range [IQR] 58.0, 77.0), 55% were Mexican American, and the median initial NIH Stroke Scale score was 3.0 (IQR 1.0, 6.0). Stroke symptom onset occurred during nocturnal sleep (25.3%), during a nap (3.9%), during wakefulness (65.9%), or unknown (4.9%). In those with SDB screening performed (n = 259), a median of 11 days (IQR 5, 17) poststroke, WUS was not associated with the presence or severity (respiratory event index) of SDB in unadjusted or adjusted analysis.ConclusionsIn this population-based study, WUS represented about 30% of all generally mild severity ischemic strokes in women and was not associated with SDB.


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