Thyroid nodules after high-dose external radiotherapy. Fine-needle aspiration cytology in diagnosis and management

JAMA ◽  
1982 ◽  
Vol 247 (23) ◽  
pp. 3217-3220 ◽  
Author(s):  
H. T. Pretorius
2006 ◽  
Vol 120 (6) ◽  
pp. 467-469 ◽  
Author(s):  
Y Bajaj ◽  
M De ◽  
A Thompson

The objective of this study was to determine the efficacy of fine needle aspiration cytology in diagnosis and management of thyroid nodules. The study also evaluated the predictive value of pre-operative fine needle aspiration cytology (FNAC) in surgical decision making, by comparing the final pathological diagnosis with the initial FNAC result.All patients who underwent thyroidectomy between 1999 and 2003 were analysed. One hundred and sixty patients who underwent pre-operative FNAC were included in this study.Fine needle aspiration was accurate in 119 (74.3 per cent) patients. Fine needle aspiration cytology and histology did not correlate in 32 (20 per cent) patients and FNAC was inadequate in nine (5.6 per cent) cases. Failures were mainly noted in cases of follicular neoplasm.Our results indicate that FNAC is helpful in the diagnosis of thyroid pathology. However, complete histopathological analysis is essential to distinguish follicular adenoma from follicular carcinoma.From this study, it can be concluded that FNAC is a cost-effective method of evaluating thyroid pathology pre-operatively and plays a useful role in planning the surgical management of thyroid nodules. However, results must be interpreted with the clinical picture in mind.


2021 ◽  
Vol 3 (5) ◽  
pp. 01-03
Author(s):  
Smaroula Divani

Objective: Although fine needle aspiration cytology (FNAC) is the most reliable, safe and accurate method for the clinical management of abnormal thyroid nodules, 5%-15% of cases lead to indeterminate diagnoses and surgery is the recommended practice for them as they may be malignant. Nevertheless, the majority of cases with indeterminate cytology are benign, so the risk of unnecessary surgery is significant. In our study we combined FNAC and scintigraphy in order to reduce the number of inappropriate surgeries. Subjects and Methods: From 219 patients with thyroid fine needle aspiration cytology 33(9 males and 24 females) aged 18-73 years, had indeterminate FNAC diagnoses and were referred for scintigraphy. Surgery was performed in all cases. The results of FNAC, scintigraphy and histology were collected and compared. Results: From 33 cases with indeterminate cytology 32 had a benign histological diagnosis and only one was malignant (follicular Ca). That case had a positive scan. All cases with negative thyroid scans (29/33) were benign. False positive scans were 3, whereas one scan was true positive with final diagnosis follicular carcinoma. Conclusion: This study showed that combining the FNAC with the thyroid scintigraphy in cases of thyroid nodules with indeterminate cytology it is possible to reduce the number of inappropriate surgeries from 32 to 3.


2017 ◽  
Vol 45 (9) ◽  
pp. 789-794 ◽  
Author(s):  
Sudarshana Roychoudhury ◽  
Fabiola Souza ◽  
Cecilia Gimenez ◽  
Ryan Glass ◽  
Rubina Cocker ◽  
...  

1990 ◽  
Vol 2 (3-4) ◽  
pp. 167-171
Author(s):  
Adel Zaki Al-Taweel ◽  
Hussein Dashti ◽  
Abdulla Behbehani ◽  
W. Olszewski ◽  
Shafik O. Atia ◽  
...  

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