Nivolumab-Associated Giant Cell Arteritis With Scalp Necrosis

2019 ◽  
Vol 155 (9) ◽  
pp. 1086 ◽  
Author(s):  
Alexander Kreuter ◽  
Bijan Koushk-Jalali ◽  
Antonino Cusenza ◽  
Frank Oellig ◽  
Christian Tigges
Keyword(s):  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Scalp Necrosis

Drug-Associated Giant Cell Arteritis with Scalp Necrosis After Treatment with Pembrolizumab: a Case Report

2022 ◽  
Vol 4 (1) ◽  
Author(s):  
Bassel Bou Dargham ◽  
Julianna Kang ◽  
Joshua Gavin ◽  
Abhishek Nandan
Keyword(s):  
Case Report ◽  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Scalp Necrosis

Scalp Necrosis Associated with Giant-Cell Arteritis

2016 ◽  
Vol 374 (6) ◽  
pp. e6 ◽  
Author(s):  
Qasim Akram ◽  
Hector Chinoy
Keyword(s):  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Scalp Necrosis

An unusual presentation of giant cell arteritis

VASA ◽  
2005 ◽  
Vol 34 (2) ◽  
pp. 128-130 ◽  
Author(s):  
Simon ◽  
Fritz ◽  
Amann-Vesti ◽  
Schenk Romer ◽  
Fischer ◽  
...  
Keyword(s):  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Nasal Septum ◽  
Rare Complication ◽  
Temporal Artery ◽  
Temporal Artery Biopsy ◽  
Elderly Persons ◽  
First Case ◽  
Scalp Necrosis ◽  
Vessel Involvement

A 77-year-old-man with giant cell arteritis who developed bitemporal scalp ulcerations is described. Since 1946 when Cooke et al. reported the first case of scalp necrosis there were approximately 55 cases published. Scalp ulceration is a rare complication of giant cell arteritis and occurs mainly in elderly persons, particularly women. About half of all patients were presented to dermatologists. Most of the patients (70%) had other serious complications of giant cell arteritis: blindness, gangrene of the tongue and nasal septum necrosis. Seventy percent of the cases were confirmed by a temporal artery biopsy. The necrosis were of varying extent and uni- or bilateral. Although, in most cases necrosis has been located bilaterally as in the presented case. Scalp healing was complete nearly in all patients by conservative treatment within a year. Scalp ulceration is a potentially reversible complication of giant cell arteritis which indicates extensive vessel involvement and adequate coricosteroid therapy is required and essential.

Scalp necrosis in giant cell arteritis: Case report and review of the relevance of this cutaneous sign of large-vessel vasculitis

2009 ◽  
Vol 61 (4) ◽  
pp. 701-706 ◽  
Author(s):  
Athanasios Tsianakas ◽  
Jan M. Ehrchen ◽  
Dagmar Presser ◽  
Tobias Fischer ◽  
Birgit Kruse-Loesler ◽  
...  
Keyword(s):  
Case Report ◽  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Large Vessel Vasculitis ◽  
Large Vessel ◽  
Scalp Necrosis

Giant Cell Arteritis with Scalp Necrosis

1978 ◽  
Vol 17 (8) ◽  
pp. 643-644 ◽  
Author(s):  
Howard D. Rosenman ◽  
Yelva Lynfield
Keyword(s):  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Scalp Necrosis

scholarly journals Scalp Necrosis Revealing Severe Giant-Cell Arteritis

2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Safa Idoudi ◽  
Marouene Ben Kahla ◽  
Fares Mselmi ◽  
Badreddine Sriha ◽  
A. Guiga ◽  
...  
Keyword(s):  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Carotid Arteries ◽  
Temporal Arteritis ◽  
Temporal Artery ◽  
The Elderly ◽  
Rare Occurrence ◽  
Irreversible Loss ◽  
Scalp Necrosis ◽  
Primary Vasculitis

Giant-cell arteritis (GCA), also referred to as temporal arteritis, is the most common primary vasculitis of the elderly involving the extracranial branches of the carotid arteries, in particular, the temporal artery. Patients usually present with temporal headaches, visual impairment, fever, and scalp tenderness. Scalp necrosis associated with GCA is a rare occurrence with approximately 100 cases reported in the literature to date. It is a therapeutic emergency requiring urgent management as it may lead to irreversible loss of vision. To increase awareness of this severe complication, we report a patient with a scalp necrosis revealing a GCA.

scholarly journals Giant Cell Arteritis Presenting as Scalp Necrosis

2011 ◽  
Vol 11 ◽  
pp. 1313-1315 ◽  
Author(s):  
Daniel E. Maidana ◽  
Silvia Muñoz ◽  
Xènia Acebes ◽  
Roger Llatjós ◽  
Anna Jucglà ◽  
...  
Keyword(s):  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Older Patients ◽  
Vision Loss ◽  
Mortality Rates ◽  
Elevated Risk ◽  
Irritant Contact Dermatitis ◽  
Scalp Necrosis ◽  
Microbial Infections ◽  
High Level

The differential of scalp ulceration in older patients should include several causes, such as herpes zoster, irritant contact dermatitis, ulcerated skin tumors, postirradiation ulcers, microbial infections, pyoderma gangrenosum, and giant cell arteritis. Scalp necrosis associated with giant cell arteritis was first described in the 1940s. The presence of this dermatological sign within giant cell arteritis represents a severity marker of this disease, with a higher mean age at diagnosis, an elevated risk of vision loss and tongue gangrene, as well as overall higher mortality rates, in comparison to patients not presenting this manifestation. Even though scalp necrosis due to giant cell arteritis is exceptional, a high level of suspicion must be held for this clinical finding, in order to initiate prompt and proper treatment and avoid blindness.

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