Human Subjects Research, Ethics, and Research on Children

Author(s):  
Loretta M. Kopelman
PLoS Medicine ◽  
2010 ◽  
Vol 7 (10) ◽  
pp. e1000349 ◽  
Author(s):  
Maria W. Merritt ◽  
Alain B. Labrique ◽  
Joanne Katz ◽  
Mahbubur Rashid ◽  
Keith P. West ◽  
...  

2019 ◽  
Vol 4 (Suppl 3) ◽  
pp. A16.3-A17
Author(s):  
Shaza Abass ◽  
Sara-Lavinia Brair ◽  
Shahd Osman ◽  
Henry Silverman

BackgroundIn Sudan, there is an increase in health research in a situation of scarce resources and limited counteractive quality assurance in research ethics. The aim of this project was to enhance the ethical review system in Sudan.MethodsOur framework for enhancing the ethical review capacity was based on the context of Sudan with emphasis on governance, coordination, feasibility, efficiency and sustainability. Activities conducted to achieve our goals included reviewing the guidelines that govern human subjects research, enhancing the governance of national authorities (National Health Research Ethics Committee and National Medicine and Poisons Board), improving coordination between the national authorities by developing a consensus clarifying their roles and functions, capacity building for the oversight bodies and institutional ethical review committees (RECs) as well as establishing a network of research ethics committees.ResultsThe guidelines that govern human subjects research in Sudan were reviewed and updated. In addition, a consensus document was endorsed to clarify the roles of the national regulatory authorities creating channels of coordination and cooperation between them and institutional RECs. Thirty-nine RECs from different parts of Sudan have been trained and the results of the pre/post test have shown an increase in the knowledge score among trainees (p<0.05). The project has also provided a platform for sharing experiences and maintaining partnerships with regional and international institutes in addition to provision of technical support for newly established RECs.ConclusionWe believe that the array of activities conducted through this project had enhanced the governance, coordination, feasibility and, efficiency of the ethical review system in Sudan.


2004 ◽  
Vol 10 (1) ◽  
pp. 105-117 ◽  
Author(s):  
Steve Drewry

This article explores the evolution of research ethics in the protection of human subjects. Included in the examination of research ethics are a brief history of twentieth-century critical incidents in human subjects research, a review of formal efforts to define the values and principles of research ethics, theoretical foundations of ethical research, and relevance to contemporary social work theory, practice, and education.Wisdom is sold in the desolate marketWhere none come to buy.—William BlakeGermany, 1948—Rudolph Helwig sits uncomfortably in the witness chair at the trial of accused Nazi scientists in Nuremberg. He is a young man, barely into his twenties, but he wears a look of perpetual fear upon his face. Helwig is afraid right now, and ashamed. Everyone in the courtroom is watching him. The prosecutor approaches the witness stand. Helwig's eyes dart to the defendants' bench, where rows of older men sit, drowsy and unperturbed. The prosecutor asks Helwig why he had been sent to Ravensbruck concentration camp in 1943. Helwig doesn't know. He is asked if he is mentally retarded. Helwig doesn't know. One of the older men smiles. The prosecutor asks Helwig why he was chosen for Ravensbruck's sterilization experiments. This Helwig knows, “I suppose it was because I could not defend myself.”


Sign in / Sign up

Export Citation Format

Share Document