scholarly journals Antiviral treatment for Bell's palsy (idiopathic facial paralysis)

Author(s):  
Ildiko Gagyor ◽  
Vishnu B Madhok ◽  
Fergus Daly ◽  
Frank Sullivan
Author(s):  
Ildiko Gagyor ◽  
Vishnu B Madhok ◽  
Fergus Daly ◽  
Dhruvashree Somasundara ◽  
Michael Sullivan ◽  
...  

Author(s):  
Yue Wan ◽  
Shugang Cao ◽  
Qi Fang ◽  
Mingfu Wang ◽  
Yi Huang

Abstract Background: Coronavirus disease 2019 (COVID-19) is a highly infectious disease, mainly causing respiratory symptoms. However, a few patients may also have neurological symptoms. Herein, we report a case of COVID-19 infection complicated with Bell’s palsy.Case presentation: A 65-year-old woman was admitted due to left facial drooping. Physical examination showed left peripheral facial paralysis. Brain MRI showed no abnormality. However, the chest CT revealed the ground-glass shadows in the right lower lung. The real-time reverse transcription-polymerase chain reaction (RT-PCR) results for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA were positive through throat swabs, while the common influenza virus antigens were tested negative. The symptoms of left facial paralysis relieved after antiviral treatment. She patient was discharged in the context of 3 consecutively negative RT-PCR test results for SARS-CoV-2 RNA and complete absorption of the right lung lesions. Conclusion: This case suggests that COVID-19 may be presented with Bell’s palsy and may be a potential cause of facial paralysis.


2015 ◽  
Vol 133 (4) ◽  
pp. 383-383 ◽  
Author(s):  
Ildiko Gagyor ◽  
Vishnu B. Madhok ◽  
Fergus Daly ◽  
Dhruvashree Somasundara ◽  
Michael Sullivan ◽  
...  

Author(s):  
Pauline Lockhart ◽  
Fergus Daly ◽  
Marie Pitkethly ◽  
Natalia Comerford ◽  
Frank Sullivan

Author(s):  
Ildiko Gagyor ◽  
Vishnu B Madhok ◽  
Fergus Daly ◽  
Dhruvashree Somasundara ◽  
Michael Sullivan ◽  
...  

Diabetes ◽  
1975 ◽  
Vol 24 (5) ◽  
pp. 449-451 ◽  
Author(s):  
K. Adour ◽  
J. Wingerd ◽  
H. E. Doty

1995 ◽  
Vol 104 (7) ◽  
pp. 574-581 ◽  
Author(s):  
Toshiaki Sugita ◽  
Yasuo Fujiwara ◽  
Shingo Murakami ◽  
Yoshinari Hirata ◽  
Naoaki Yanagihara ◽  
...  

We have been the first to succeed in producing an acute and transient facial paralysis simulating Bell's palsy, by inoculating herpes simplex virus into the auricles or tongues of mice. The KOS strain of the virus was injected into the auricle of 104 mice and the anterior two thirds of the tongue in 30 mice. Facial paralysis developed between 6 and 9 days after virus inoculation, continued for 3 to 7 days, and then recovered spontaneously. The animals were painlessly sacrificed between 6 and 20 days after inoculation for histopathologic and immunocytochemical study. Histopathologically, severe nerve swelling, inflammatory cell infiltration, and vacuolar degeneration were manifested in the affected facial nerve and nuclei. Herpes simplex virus antigens were also detected in the facial nerve, geniculate ganglion, and facial nerve nucleus. The pathophysiologic mechanisms of the facial paralysis are discussed in light of the histopathologic findings, in association with the causation of Bell's palsy.


2021 ◽  
Vol 10 (20) ◽  
pp. 1551-1554
Author(s):  
Vrushali K. Athawale ◽  
Dushyant P. Bawiskar ◽  
Pratik Arun Phansopkar

Facial nerve palsy is the disease of cranial nerve. From the total number of cases, 60 to 75 % of Bell's palsy cases are idiopathic form of facial palsy. Facial nerve palsy results in weakness of facial muscles, atrophy, asymmetry of face and also disturbs the quality of life. Bell’s palsy occurs in every class of population affecting people of all the age groups but the most common age group affected is 15 - 50 years with equal sex prediliction accounting 11 - 40 cases per 100,000. If facial palsy is not treated properly then it may result in variety of complications like motor synkinesis, dysarthria, contractures of facial muscles, and crocodile tear. Currently facial paralysis treatment consists of combination of pharmacological therapy, facial neuromuscular re-entrainment physiotherapy or surgical intervention by static and dynamic facial reanimation techniques. Physiotherapy treatment is effective for treating facial paralysis with minimal complications and can be individualized. Bell's palsy is the idiopathic form of facial nerve palsy which accounts for 60 to 75 % of cases and male to female ratio is 1:3.1 The aetiology of facial paralysis is not yet thoroughly understood. Cases of varicella-zoster, mononucleosis, herpes simplex virus, mumps and measles have demonstrated good serology in several reports for their association but still stands unclear. 2 Peripheral facial nerve palsy may be idiopathic (primary cause) or Bell’s palsy (secondary). Causes of the secondary unilateral facial nerve palsy are diabetes, stroke, Hansen's disease, herpes simplex infection, birth injury, trauma, tumour, Guillain-Barre syndrome, and immune system disorders. Causes of the bilateral facial nerve palsy are leukemia, brainstem encephalitis, leprosy, and meningitis. The most prominent current theories of facial nerve paralysis pathophysiology include the reactivation of herpes simplex virus infection (HSV type 1). Current facial paralysis treatment consists of a combination of pharmacological therapy, facial neuromuscular re-entrainment physiotherapy or surgical intervention by dynamic and static facial reanimation techniques.7 This is a diagnosed case of right facial nerve palsy which was treated under physiotherapy department with proper rehabilitation protocol.


Sign in / Sign up

Export Citation Format

Share Document