Animals in flow – Towards the scientific study of intrinsic reward in animals

The concept of flow, a state of complete absorption in an intrinsically rewarding activity, has played a pivotal role in advancing notions of human well-being beyond minimising suffering towards promoting flourishing and thriving. While flow has played a fundamental role in human positive psychology, it has not yet been explored in non-human animals, leaving an enormous void in our understanding of intrinsic motivation in animals. As ethology and related fields keep progressing in uncovering complex cognitive and affective capacities of non-human animals, we propose the time is ripe to translate the concept of flow to animals. We start by embedding flow in the topic of intrinsic motivation and describe its impact on positive human psychology and potentially positive animal welfare. We then disambiguate flow from related concepts discussed in the animal literature. Next, we derive experimental approaches in animals from the canonical characteristics of flow in humans and provide guidelines for both inducing and assessing flow by focusing on two characteristics that do not necessarily depend on self-report, namely resistance to distraction and time distortion. Not all aspects of the human flow experience are (yet) translatable, but those that are may improve quality of life in non-human animals.

ANALYSIS OF THE EFFICIENCY OF ACOUSTIC SCREENS OF DIFFERENT DESIGNS

Various sources of noise in cities and ways to combat them are considered. The effi ciency of two types of acoustic screens is analyzed: single-layer and two-and three-layer. The positive and negative characteristics of various designs of existing acoustic screens are listed. A fundamentally new design of the acoustic screen is described: the panels have a ridge profi le, they are located along the vertical axis of the frame with a step at which the panels above the located ridge cover the top of the lower ridge, the outer surfaces of the panels and their end parts are made of a material that has sound-refl ecting properties, and the inner surfaces of the panels are made of sound-absorbing material. Such an acoustic screen is devoid of the disadvantages inherent in acoustic screens of other structures and is more effi cient. The considered invention allows due to the use of the ridge shape of acoustic panels: prevent the refl ection of sound energy in the direction of noise sources (a small part will be directed upwards); provide almost complete absorption of sound energy as it passes through the channels formed by the ridge panels; provide the same effective protection against noise sources located on both sides of the screen; prevent the formation of snow and ice crust on sound-absorbing surfaces, which ensures the constant eff ectiveness of the screen in diff erent seasons of the year; reduce metal consumption, which will reduce the weight of the structure without reducing its effi ciency and reduce the cost of acoustic screens.

High-Quality Graphene-Based Tunable Absorber Based on Double-Side Coupled-Cavity Effect

Graphene-based devices have important applications attributed to their superior performance and flexible tunability in practice. In this paper, a new kind of absorber with monolayer graphene sandwiched between two layers of dielectric rings is proposed. Two peaks with almost complete absorption are realized. The mechanism is that the double-layer dielectric rings added to both sides of the graphene layer are equivalent to resonators, whose double-side coupled-cavity effect can make the incident electromagnetic wave highly localized in the upper and lower surfaces of graphene layer simultaneously, leading to significant enhancement in the absorption of graphene. Furthermore, the influence of geometrical parameters on absorption performance is investigated in detail. Also, the device can be actively manipulated after fabrication through varying the chemical potential of graphene. As a result, the frequency shifts of the two absorption peaks can reach as large as 2.82 THz/eV and 3.83 THz/eV, respectively. Such a device could be used as tunable absorbers and other functional devices, such as multichannel filters, chemical/biochemical modulators and sensors.

Label-Free Complete Absorption Microscopy Using Second Generation Photoacoustic Remote Sensing

In the past decades, absorption modalities have emerged as powerful tools for label-free functional and structural imaging of cells and tissues. Many biomolecules present unique absorption spectra providing chromophore-specific information on properties such as chemical bonding, and sample composition. As chromophores absorb photons the absorbed energy is emitted as photons (radiative relaxation) or converted to heat and under specific conditions pressure (non-radiative relaxation). Modalities like fluorescence microscopy may capture radiative relaxation to provide contrast, while modalities like photoacoustic microscopy may leverage non-radiative heat and pressures. Here we show an all-optical non-contact total-absorption photoacoustic remote sensing (TA-PARS) microscope, which can capture both radiative and non-radiative absorption effects in a single acquisition. The TA-PARS yields an absorption metric proposed as the quantum efficiency ratio (QER), which visualizes a biomolecules proportional radiative and non-radiative absorption response. The TA-PARS provides label-free visualization of a range of biomolecules enabling convincing analogues to traditional histochemical staining of tissues, effectively providing label-free Hematoxylin and Eosin (H&E)-like visualizations. These findings represent the establishment of an effective all-optical non-contact total-absorption microscope for label-free inspection of biological media.

‘Soother of mind’ – meditation in psychiatric disorders: a narrative review

SUMMARY Meditation, a component of ashtanga yoga, is an act of inward contemplation in which the mind fluctuates between a state of attention to a stimulus and complete absorption in it. Some forms of meditation have been found to be useful for people with psychiatric conditions such as anxiety, depression and substance use disorder. Evidence for usefulness of meditation for people with psychotic disorders is mixed, with reported improvements in negative symptoms but the emergence/precipitation of psychotic symptoms. This article narrates the benefits of meditation in psychiatric disorders, understanding meditation from the yoga perspective, biological aspects of meditation and practical tips for the practice of meditation. We also explain possible ways of modifying meditative practices to make them safe and useful for the patient population and useful overall as a society-level intervention.

Pharmacokinetic Behaviour of Enrofloxacin after Single Intramuscular Dosage in American Black Vultures (Coragyps atratus)

The aim of the study was to investigate the intramuscular pharmacokinetics of enrofloxacin in black vultures (Coragyps atratus). The pharmacokinetics of a single intramuscular dose (10 mg/kg) of enrofloxacin was studied in six vultures. Plasma concentrations of enrofloxacin and its active metabolite, ciprofloxacin, were determined by high-performance liquid chromatography (HPLCuv). Pharmacokinetic parameters were estimated using non-compartmental and compartmental analysis. After intramuscular administration, enrofloxacin showed a rapid and complete absorption, reaching a Cmax value of 3.26 ± 0.23 μg/mL at 1.75 ± 0.53 h. A long terminal half-life of 19.58 h has been observed. Using previously published MIC values to perform a PK/PD analysis, cumulative fraction responses obtained after Monte Carlo simulation for AUC/MIC > 30, 50 and 125 were 72.93%, 72.34% and 30.86% for E. coli and 89.29%, 88.89% and 58.57% for Mycoplasma synoviae, respectively. Cumulative fraction responses obtained for Cmax/MIC index were 33.93% and 40.18% for E. coli and M. synoviae, respectively. The intramuscular administration of 10 mg/kg could be appropriate to treat infectious diseases caused by gram-positive bacteria with MIC value lower than 1 µg/mL; however, although enrofloxacin showed a slow elimination in black vultures, plasma concentrations were insufficient to reach the gram-negative stablished breakpoints.

Magnetic Oil Sorbents based on Technogenic and Natural Inorganic Materials

The results of the study of the fractional composition, physicochemical and sorption characteristics of technological calcium carbonate and glauconite are presented. It is shown that the fraction of technological chalk with a particle size of more than 0.125 mm absorbs the greatest amount of oil and gasoline. The oil is better absorbed by the fraction of chalk with a particle size of 0.1–0.25 mm. For glauconite, oil sorption increases with decreasing particle size. The complete absorption of oil on the solid surface by the glauconite sorbent occurred within 2 min and about 10 min by the carbonate sorbent; the recovery rates were 99% and 90%, respectively. The best results in terms of the degree of water purification from oil were shown by a carbonate sorbent with a particle size of more than 0.125 mm – 83 % and glauconite with a particle size of 0.045–0.1 mm – 90% with an oil film thickness of 0.5 mm. The degree of water purification from oil was 80 % for the carbonate sorbent and 93 % for the glauconite one with an oil film thickness of 0.5 mm. With an increase in the thickness of the oil and oil films, the degree of water purification decreases.

AESTHETIC EXPERIENCE AND AESTHETIC JUDGMENTS: THE FEATURES OF THE RELATIONSHIPS

The article examines the essence and relationship of aesthetic experience and aesthetic judgment. It is argued that philosophical aesthetics deals with constants that are fundamental to aesthetic experience. Such constants are phenomena and characteristics that have a fundamental ontological status in the aesthetic sphere. It was found that the ontological characteristic of aesthetic experience is that it is not reducible to “pure” rationality, that is, it is not something that is “adapted” to complete and final comprehension by the mind alone. Therefore, a complete “absorption” of aesthetic experience by a certain semantic structure is impossible: such experience always goes beyond any discursive boundaries and simultaneously opens them. In addition, aesthetic experience serves as one of the means of a person’s “contact” with the world and society. Forming on the material of sensations, aesthetic experience extends from the most general ideas about the universe to the inner life of a person. The analysis also showed that the formulation of an aesthetic judgment is based on the concepts of the perfect and the imperfect. In turn, the mastery of such concepts is carried out in the process of correlating a certain aesthetic fact with the existing value scale. That is why aesthetic judgments have signs of normativity. They also create the basis for a common worldview and attitude, lay the foundation for mutual understanding between people of a certain culture. The study showed that the process of aesthetic assessment is a constant correlation of the existing state of affairs with something ideal (within a certain value scale), this is a permanent “demand” for perfection, as well as a tireless search for an opportunity to fulfill this “demand”. At the same time, ethical experience is dissociated from “pure” pragmatics, which personifies vital necessity, because the aesthetic sphere is always associated with a certain “redundancy” in human existence. Also, the results obtained in the course of the study suggested that philosophical aesthetics, which takes into account and investigates the specificity of the phenomenon of corporeality, as well as such phenomena of human existence as affective sensitivity and sensitive rationality, is able to overcome the limitation of “an-esthetic” naturalism in aesthetics.