Alkane Functionalization by Metal‐Catalyzed Carbene Insertion from Diazo Reagents

2021 ◽  
pp. 1-24
Author(s):  
María Álvarez ◽  
Ana Caballero ◽  
Pedro J. Pérez
Keyword(s):  
Alkane Functionalization ◽  
Carbene Insertion ◽  
Diazo Reagents ◽  
Metal Catalyzed

A stereocontrolled, enantiomerically specific total synthesis of thienamycin

1980 ◽  
Vol 289 (1036) ◽  
pp. 191-195 ◽  
Keyword(s):  
Total Synthesis ◽  
Aspartic Acid ◽  
Ring System ◽  
Insertion Reaction ◽  
Carbene Insertion ◽  
Metal Catalyzed

A versatile stereocontrolled total synthesis of thienamycin starting from L-aspartic acid is reported. Stereocontrol is achieved by potassium tri- sec -butylborohydride reduction of a thermodynamically formed 3α-acetylazetidinone intermediate. The key [3.2.0] bicyclic ring system is prepared by a metal catalyzed carbene insertion reaction.

Chiral proton-transfer shuttle catalysts for carbene insertion reactions

2018 ◽  
Vol 16 (17) ◽  
pp. 3087-3094 ◽  
Author(s):  
Yuan-Yuan Ren ◽  
Shou-Fei Zhu ◽  
Qi-Lin Zhou
Keyword(s):  
Transition Metal ◽  
Proton Transfer ◽  
Insertion Reactions ◽  
Carbene Insertion ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

The development of chiral proton-transfer shuttles provides a totally new enantiocontrol strategy for transition metal-catalyzed asymmetric carbene insertion reactions.

A New Perfluorinated F21-Tp Scorpionate Ligand: Enhanced Alkane Functionalization by Carbene Insertion with (F21-Tp)M Catalysts (M = Cu, Ag)

2008 ◽  
Vol 27 (18) ◽  
pp. 4779-4787 ◽  
Author(s):  
Emmanuelle Despagnet-Ayoub ◽  
Kane Jacob ◽  
Laure Vendier ◽  
Michel Etienne ◽  
Eleuterio Álvarez ◽  
...  
Keyword(s):  
Alkane Functionalization ◽  
Carbene Insertion ◽  
Scorpionate Ligand

Rhodium-catalyzed coupling of arenes and fluorinated α-diazo diketones: synthesis of chromones

2020 ◽  
Vol 56 (86) ◽  
pp. 13169-13172
Author(s):  
Jiayi Yao ◽  
Lingheng Kong ◽  
Xingwei Li
Keyword(s):  
Nucleophilic Aromatic Substitution ◽  
Aromatic Substitution ◽  
Carbene Insertion ◽  
Diazo Reagents

Rh(iii)-Catalyzed synthesis of chromones using arenes and fluorinated diazo reagents via C–H activation, carbene insertion, and uncatalyzed intramolecular nucleophilic aromatic substitution.

Catalytic asymmetric synthesis of cyclopropylphosphonates — Catalysts' scope and reactivity

2005 ◽  
Vol 83 (6-7) ◽  
pp. 533-542 ◽  
Author(s):  
André B Charette ◽  
Jean-Emmanuel Bouchard
Keyword(s):  
Transition Metal ◽  
Asymmetric Synthesis ◽  
Copper Catalysts ◽  
Ruthenium Catalysts ◽  
Catalytic Asymmetric Synthesis ◽  
Reaction Proceeds ◽  
Transition Metal Catalyzed ◽  
Diazo Reagents ◽  
Metal Catalyzed ◽  
High Yields

The transition metal-catalyzed cyclopropanation of alkenes using α-diazomethylphosphonates leads to cyclopropylphosphonate derivatives in high yields. The reaction proceeds well with copper, rhodium, and ruthenium catalysts. The best catalysts for the enantioselective version are either Evans' Cu·bis(oxazoline) or Nishiyama's Ru·pybox.Key words: cyclopropylphosphonic acids, copper catalysts, ruthenium catalysts, cyclopropanation, diazo reagents.

scholarly journals Recent Advance in the Transition-Metal-Catalyzed Carbene Insertion Reactionsof Si—H Bond

2020 ◽  
Vol 40 (4) ◽  
pp. 873
Author(s):  
Huimiao Zhang ◽  
Lingzhi Li ◽  
Fangqi Shen ◽  
Tao Cai ◽  
Runpu Shen
Keyword(s):  
Transition Metal ◽  
Carbene Insertion ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed
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