scholarly journals Manganese Ferrite Nanoparticles Encapsulated into Vitamin E/Sphingomyelin Nanoemulsions as Contrast Agents for High‐Sensitive Magnetic Resonance Imaging

2021 ◽  
pp. 2101019
Author(s):  
Sandra Díez‐Villares ◽  
Miguel A. Ramos‐Docampo ◽  
Andrés da Silva‐Candal ◽  
Pablo Hervella ◽  
Abi J. Vázquez‐Ríos ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Vitamin E ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Ferrite Nanoparticles ◽  
Manganese Ferrite ◽  
Resonance Imaging

Chitosan-coated nickel-ferrite nanoparticles as contrast agents in magnetic resonance imaging

2015 ◽  
Vol 381 ◽  
pp. 151-157 ◽  
Author(s):  
Tanveer Ahmad ◽  
Hongsub Bae ◽  
Yousaf Iqbal ◽  
Ilsu Rhee ◽  
Sungwook Hong ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Nickel Ferrite ◽  
Ferrite Nanoparticles ◽  
Resonance Imaging ◽  
Nickel Ferrite Nanoparticles

Water-soluble superparamagnetic manganese ferrite nanoparticles for magnetic resonance imaging

Biomaterials ◽  
2010 ◽  
Vol 31 (13) ◽  
pp. 3667-3673 ◽  
Author(s):  
Hong Yang ◽  
Cuixia Zhang ◽  
Xiangyang Shi ◽  
He Hu ◽  
Xiaoxia Du ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Ferrite Nanoparticles ◽  
Water Soluble ◽  
Manganese Ferrite ◽  
Resonance Imaging

Rod-Shaped Dextran-Coated Nickel-Ferrite Nanoparticles for Use as Contrast Agents in Magnetic Resonance Imaging

2018 ◽  
Vol 68 (3) ◽  
pp. 290-295
Author(s):  
Da-Ae LEE ◽  
Yusaf IQBAL ◽  
Hongsub BAE ◽  
Ilsu RHEE* ◽  
Sungwook HONG
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Nickel Ferrite ◽  
Ferrite Nanoparticles ◽  
Resonance Imaging ◽  
Nickel Ferrite Nanoparticles

Ultrasmall Manganese Ferrite Nanoparticles as Positive Contrast Agent for Magnetic Resonance Imaging

2013 ◽  
Vol 2 (7) ◽  
pp. 958-964 ◽  
Author(s):  
Zhen Li ◽  
Shu Xia Wang ◽  
Qiao Sun ◽  
Hong Li Zhao ◽  
Hao Lei ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
Positive Contrast ◽  
Ferrite Nanoparticles ◽  
Manganese Ferrite ◽  
Resonance Imaging

scholarly journals Ultrasmall Manganese Ferrites as Multimodal Bioimaging Agents and Fenton/Haber-Weiss Catalysts

2020 ◽  
Author(s):  
Susana Carregal-Romero ◽  
Ana Beatriz Miguel-Coello ◽  
Lydia Martínez-Parra ◽  
Yilian Fernández-Afonso ◽  
Sandra Plaza ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Catalytic Properties ◽  
Strong Dependence ◽  
Ferrite Nanoparticles ◽  
Manganese Ferrite ◽  
Resonance Imaging ◽  
Substantial Impact ◽  
Mn Doping ◽  
Wide Range

<p>Ultrasmall<b> </b>manganese ferrite nanoparticles display interesting features in bioimaging and Fenton nanocatalysis. However, little is known about how to optimize these nanoparticles to achieve simultaneously the highest efficiency in both types of applications. Herein, we present a cost-efficient synthetic microwave method that enables manganese ferrite nanoparticles to be produced with excellent control in size, chemical composition and colloidal stability. We show how the reaction’s pH has a substantial impact on the Mn incorporation into the nanoparticles and the level of Mn doping can be finely tailored to a wide range (Mn<sub>x</sub>Fe<sub>3-x</sub>O<sub>4</sub>, 0.1 ≤ x ≤ 2.4). The magnetic relaxivities (1.6 ≤ r<sub>1 </sub>≤ 10.6 mM<sup>-1</sup>s<sup>-1</sup> and (7.5 ≤ r<sub>2 </sub>≤ 29.9 mM<sup>-1</sup>s<sup>-1</sup>) and Fenton/Haber-Weiss catalytic properties measured for the differently doped nanoparticles show a strong dependence on the Mn content and, interestingly, on the synthetic reaction’s pH. Positive contrast in magnetic resonance imaging is favored by low Mn contents, while dual mode magnetic resonance imaging contrast and catalytic activity increases in nanoparticles with a high degree of Mn doping. We show that this is valid in solution, in a murine model and intracellularly respectively. Besides, this synthetic protocol allows core-radiolabeling for high-sensitive molecular imaging while maintaining relaxometric and catalytic properties. All of these results show the robust characteristics of these multifunctional manganese ferrite nanoparticles as theranostic agents.</p>

scholarly journals Ultrasmall Manganese Ferrites as Multimodal Bioimaging Agents and Fenton/Haber-Weiss Catalysts

2020 ◽  
Author(s):  
Susana Carregal-Romero ◽  
Ana Beatriz Miguel-Coello ◽  
Lydia Martínez-Parra ◽  
Yilian Fernández-Afonso ◽  
Sandra Plaza ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Catalytic Properties ◽  
Strong Dependence ◽  
Ferrite Nanoparticles ◽  
Manganese Ferrite ◽  
Resonance Imaging ◽  
Substantial Impact ◽  
Mn Doping ◽  
Wide Range

<p>Ultrasmall<b> </b>manganese ferrite nanoparticles display interesting features in bioimaging and Fenton nanocatalysis. However, little is known about how to optimize these nanoparticles to achieve simultaneously the highest efficiency in both types of applications. Herein, we present a cost-efficient synthetic microwave method that enables manganese ferrite nanoparticles to be produced with excellent control in size, chemical composition and colloidal stability. We show how the reaction’s pH has a substantial impact on the Mn incorporation into the nanoparticles and the level of Mn doping can be finely tailored to a wide range (Mn<sub>x</sub>Fe<sub>3-x</sub>O<sub>4</sub>, 0.1 ≤ x ≤ 2.4). The magnetic relaxivities (1.6 ≤ r<sub>1 </sub>≤ 10.6 mM<sup>-1</sup>s<sup>-1</sup> and (7.5 ≤ r<sub>2 </sub>≤ 29.9 mM<sup>-1</sup>s<sup>-1</sup>) and Fenton/Haber-Weiss catalytic properties measured for the differently doped nanoparticles show a strong dependence on the Mn content and, interestingly, on the synthetic reaction’s pH. Positive contrast in magnetic resonance imaging is favored by low Mn contents, while dual mode magnetic resonance imaging contrast and catalytic activity increases in nanoparticles with a high degree of Mn doping. We show that this is valid in solution, in a murine model and intracellularly respectively. Besides, this synthetic protocol allows core-radiolabeling for high-sensitive molecular imaging while maintaining relaxometric and catalytic properties. All of these results show the robust characteristics of these multifunctional manganese ferrite nanoparticles as theranostic agents.</p>

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