Antiinflammatory and antifibrotic effects of the oral direct thrombin inhibitor dabigatran etexilate in a murine model of interstitial lung disease

Thrombin Inhibitor ◽

Dabigatran Etexilate, An Oral Direct Thrombin Inhibitor, Represses Fibrotic Changes In A Murine Model Of Pulmonary Fibrosis

10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a6780 ◽

2010 ◽

Author(s):

Richard M. Silver ◽

Anna Ludwicka-Bradley ◽

Paul Nietert ◽

Joanne van Ryn ◽

Galina S. Bogatkevich

Keyword(s):

Pulmonary Fibrosis ◽

Murine Model ◽

Dabigatran Etexilate ◽

Thrombin Inhibitor ◽

The Oral Direct Thrombin Inhibitor, Dabigatran Etexilate, is Effective and Safe for Prevention of Major Venous Thromboembolism After Major Orthopedic Surgery

The Journal of Arthroplasty ◽

10.1016/j.arth.2008.01.242 ◽

2008 ◽

Vol 23 (2) ◽

pp. 320

Author(s):

Michael H. Huo ◽

Joseph Caprini ◽

Stefan Hantel ◽

Janet Schnee

Keyword(s):

Venous Thromboembolism ◽

Orthopedic Surgery ◽

Dabigatran Etexilate ◽

Thrombin Inhibitor ◽

Oral Direct Thrombin Inhibitor ◽

Major Orthopedic Surgery

Dabigatran etexilate: an oral direct thrombin inhibitor

Therapy ◽

10.2217/14750708.5.5.685 ◽

2008 ◽

Vol 5 (5) ◽

pp. 685-695 ◽

Cited By ~ 8

Author(s):

Ola E Dahl

Keyword(s):

Dabigatran Etexilate ◽

Thrombin Inhibitor ◽

Dabigatran Etexilate: An Oral Direct Thrombin Inhibitor for the Management of Thromboembolic Disorders

Clinical Therapeutics ◽

10.1016/j.clinthera.2012.02.022 ◽

2012 ◽

Vol 34 (4) ◽

pp. 766-787 ◽

Cited By ~ 13

Author(s):

Judy W.M. Cheng ◽

Huyen Vu

Keyword(s):

Dabigatran Etexilate ◽

Thrombin Inhibitor ◽

Pharmacokinetics and Pharmacodynamics of Dabigatran Etexilate, an Oral Direct Thrombin Inhibitor, With Coadministration of Digoxin

The Journal of Clinical Pharmacology ◽

10.1177/0091270010393342 ◽

2012 ◽

Vol 52 (2) ◽

pp. 243-250 ◽

Cited By ~ 31

Author(s):

Joachim Stangier ◽

Hildegard Stähle ◽

Karin Rathgen ◽

Willy Roth ◽

Kathrin Reseski ◽

...

Keyword(s):

Dabigatran Etexilate ◽

Thrombin Inhibitor ◽

Pharmacokinetics And Pharmacodynamics ◽

A new oral direct thrombin inhibitor, dabigatran etexilate, compared with enoxaparin for prevention of thromboembolic events following total hip or knee replacement: the BISTRO II randomized trial

Journal of Thrombosis and Haemostasis ◽

10.1111/j.1538-7836.2004.01100.x ◽

2005 ◽

Vol 3 (1) ◽

pp. 103-111 ◽

Cited By ~ 294

Author(s):

B. I. ERIKSSON ◽

O. E. DAHL ◽

H. R. BULLER ◽

R. HETTIARACHCHI ◽

N. ROSENCHER ◽

...

Keyword(s):

Randomized Trial ◽

Knee Replacement ◽

Dabigatran Etexilate ◽

Prevention Of Thromboembolic Events

Thrombin Inhibitor ◽

Thromboembolic Events ◽

Oral Direct Thrombin Inhibitor ◽

Total Hip ◽

The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects

British Journal of Clinical Pharmacology ◽

10.1111/j.1365-2125.2007.02899.x ◽

2007 ◽

Vol 64 (3) ◽

pp. 292-303 ◽

Cited By ~ 608

Author(s):

Joachim Stangier ◽

Karin Rathgen ◽

Hildegard Stähle ◽

Dietmar Gansser ◽

Willy Roth

Keyword(s):

Dabigatran Etexilate ◽

Thrombin Inhibitor ◽

Healthy Male ◽

Oral Direct Thrombin Inhibitor ◽

Male Subjects

Pharmacokinetics and Pharmacodynamics of Dabigatran Etexilate, an Oral Direct Thrombin Inhibitor, Are Not Affected by Moderate Hepatic Impairment

The Journal of Clinical Pharmacology ◽

10.1177/0091270008324179 ◽

2008 ◽

Vol 48 (12) ◽

pp. 1411-1419 ◽

Cited By ~ 111

Author(s):

Joachim Stangier ◽

Hildegard Stähle ◽

Karin Rathgen ◽

Willy Roth ◽

Kasra Shakeri-Nejad

Keyword(s):

Hepatic Impairment ◽

Dabigatran Etexilate ◽

Thrombin Inhibitor ◽

Moderate Hepatic Impairment ◽

Pharmacokinetics And Pharmacodynamics ◽

Dabigatran Etexilate: An Oral Direct Thrombin Inhibitor for Prophylaxis and Treatment of Thromboembolic Diseases

Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy ◽

10.1592/phco.28.11.1354 ◽

2008 ◽

Vol 28 (11) ◽

pp. 1354-1373 ◽

Cited By ~ 73

Author(s):

Brooke E Baetz ◽

Sarah A Spinler

Keyword(s):

Dabigatran Etexilate ◽

Thrombin Inhibitor ◽

Therapeutic Promise of Dabigatran Etexilate, an Oral Direct Thrombin Inhibitor in a Preclinical Model of Colon Carcinogenesis

Clinical and Experimental Pharmacology ◽

10.4172/2161-1459.1000247 ◽

2018 ◽

Vol 08 (02) ◽

Author(s):

Sangole PN ◽

Majumdar AS

Keyword(s):

Dabigatran Etexilate ◽

Colon Carcinogenesis ◽

Thrombin Inhibitor ◽

Preclinical Model ◽