scholarly journals From preclinical to human - prediction of oral absorption and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach in an industrial setting: a workflow by using case example

2012 ◽  
Vol 33 (2) ◽  
pp. 111-121 ◽  
Author(s):  
Vikash Kumar Sinha ◽  
Jan Snoeys ◽  
Nancy Van Osselaer ◽  
Achiel Van Peer ◽  
Claire Mackie ◽  
...  
Keyword(s):  
Drug Interaction ◽  
Interaction Potential ◽  
Oral Absorption ◽  
Pbpk Modeling ◽  
Modeling Approach ◽  
Physiologically Based Pharmacokinetic ◽  
Industrial Setting ◽  
Physiologically Based ◽  
Drug Drug Interaction

scholarly journals In vitro and physiologically‐based pharmacokinetic based assessment of drug–drug interaction potential of canagliflozin

2016 ◽  
Vol 83 (5) ◽  
pp. 1082-1096 ◽  
Author(s):  
Rao N. V. S. Mamidi ◽  
Shannon Dallas ◽  
Carlo Sensenhauser ◽  
Heng Keang Lim ◽  
Ellen Scheers ◽  
...  
Keyword(s):  
Drug Interaction ◽  
Interaction Potential ◽  
Physiologically Based Pharmacokinetic ◽  
Physiologically Based ◽  
Drug Drug Interaction

scholarly journals A Novel PBPK Modeling Approach to Assess Cytochrome P450 Mediated Drug-Drug Interaction Potential of the Cytotoxic Prodrug Evofosfamide

2018 ◽  
Vol 7 (12) ◽  
pp. 829-837 ◽  
Author(s):  
Christian Lüpfert ◽  
Martin Dyroff ◽  
Oliver von Richter ◽  
Dieter Gallemann ◽  
Samer El Bawab ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Drug Interaction ◽  
Interaction Potential ◽  
Pbpk Modeling ◽  
Modeling Approach ◽  
Drug Drug Interaction
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