Emodin Prevents Ethanol-Induced Developmental Anomalies in Cultured Mouse Fetus through Multiple Activities

2013 ◽  
Vol 98 (3) ◽  
pp. 268-275 ◽  
Author(s):  
Jung-Min Yon ◽  
Chunmei Lin ◽  
Ki-Wan Oh ◽  
Hong-Seok Baek ◽  
Beom Jun Lee ◽  
...  
Keyword(s):  
Mouse Fetus ◽  
Developmental Anomalies

Developmental Anomalies of the WAIS-IV Digit Span Subtest

2013 ◽  
Author(s):  
Helen H. Hansen ◽  
Joel Simons ◽  
Wayne V. Adams ◽  
Jeffrey Schloemer ◽  
Jenae Ulrich
Keyword(s):  
Digit Span ◽  
Developmental Anomalies

Effects of Fetus Weight, Dam Strain, Dam Weight, and Litter Size on the Craniofacial Morphogenesis of CL/Fr Mouse Fetuses Affected with Cleft Lip and Palate

1997 ◽  
Vol 34 (4) ◽  
pp. 325-330 ◽  
Author(s):  
Kazuaki Nonaka ◽  
Yasunori Sasaki ◽  
Yoshihisa Watanabe ◽  
Ken-ichi Yanagita ◽  
Minoru Nakata
Keyword(s):  
Litter Size ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Craniofacial Morphology ◽  
Strain Effect ◽  
Craniofacial Growth ◽  
Lateral Cephalogram ◽  
Mouse Fetus ◽  
Mouse Fetuses ◽  
Craniofacial Morphogenesis

Objective: This study examined the factors related to the morphogenesis of the craniofacial complex of the CL/Fr mouse fetus affected with CLP based on the findings of a lateral cephalogram. Design: Embryo transfer experiments were performed to determine the effect of the fetus weight, dam strain, dam weight, and litter size on the intra-uterine craniofacial morphogenesis of CL/Fr mouse fetuses. On the 18th gestational day, each pregnant dam that had received CL/Fr mouse embryos was laparotomized to remove the transferred fetuses that had developed in the uteri of the cleft lip and palate (CLP)-susceptible CL/Fr strain dam and the CLP-resistant C57BL strain dam. A cephalometric observation of the craniofacial morphology of each fetus was subsequently performed. Results: Based on a multiple regression analysis, the standardized partial regression coefficients of the affected fetus weight, the dam weight, and the litter size on the maxillary size of the affected CL/Fr fetus were 0.71 (p < .01), 0.03, and −0.07. According to a least-squares analysis of variance, the dam strain effect in addition to the effect of the affected fetus weight on the maxillary size and the cranial size of the affected fetuses was significant (p < .01 for cranial size, p < .05 for maxillary size) and close to a significant level (p = .09) for the mandibular size of the affected fetuses. The adjusted maxillary size and cranial size after statistically eliminating the effects of the affected fetus weight, dam weight, and lifter size on each original craniofacial size of the affected fetuses that had developed in the CL/Er dam strain were also significantly smaller than those of the affected fetuses that had developed in the C57BL dam strain. Conclusions: The present results indicate that the craniofacial growth of the CL/Fr mouse fetus affected with CLP increased in proportion to the fetus weight. The dam strain effect, in addition to the effect of the affected fetus weight, could thus not be ignored when the etiology of the spontaneous CLP was examined, while the uterine environment, provided by the CL/Fr strain dam, retarded the intra-uterine craniofacial growth of the affected fetuses. It was therefore concluded that the dam strain effect, as well as the effect of the affected fetus weight, both play an important role on the craniofacial morphogenesis of the CL/Fr strain of the affected fetuses that developed in both strain dams.

Drosophila NSD deletion induces developmental anomalies similar to those seen in Sotos syndrome 1 patients

2021 ◽  
Author(s):  
Saeyan Choi ◽  
Bokyeong Song ◽  
Hyewon Shin ◽  
Chihyun Won ◽  
Taejoon Kim ◽  
...  
Keyword(s):  
Sotos Syndrome ◽  
Developmental Anomalies

Teratogenic Effects of Sodium Valproate in the Jcl: ICR Mouse Fetus

1990 ◽  
Vol 32 (5) ◽  
pp. 502-507 ◽  
Author(s):  
Tohru Sonoda ◽  
Shozo Ohdo ◽  
Ken-ichi Ohba ◽  
Takahiro Okishima ◽  
Kunio Hayakawa
Keyword(s):  
Sodium Valproate ◽  
Teratogenic Effects ◽  
Mouse Fetus ◽  
Icr Mouse

Developmental Anomalies of Permanent Lateral Incisors in Young Patients

2009 ◽  
Vol 33 (3) ◽  
pp. 211-216 ◽  
Author(s):  
Yuko Fujita ◽  
Akiko Hidaka ◽  
Ikuko Nishida ◽  
Kazumasa Morikawa ◽  
Daisuke Hashiguchi ◽  
...  
Keyword(s):  
Young Patients ◽  
Pediatric Dentistry ◽  
Optimal Time ◽  
Prevalence Rates ◽  
Supernumerary Tooth ◽  
Japanese Children ◽  
College Hospital ◽  
Developmental Anomalies ◽  
Dental Clinics ◽  
Appropriate Treatment

Objective: To elucidate the prevalence of developmental anomalies of permanent lateral incisors among young patients in Japan. Study deign: A total of 1375 patients were observed between 1990 and 2008 at the Department of Pediatric Dentistry in the Kyushu Dental College Hospital and four private pediatric dental clinics in Kitakyushu City. Panoramic and periapical radiographs were examined for all those patients aged 5 to 19 years. Results: The prevalence of agenesis of the lateral incisors was 7.3% (100 patients), with more girls than boys being affected. The prevalence rates of absent upper and lower lateral incisors were 2.7 and 4.8 % (34 and 63 patients), respectively. Nine (0.7 %) of the total patients had microdontia. Eruption disturbance was present in five patients (0.4 %). Two of five patients presented with a disturbed eruption owing to an odontoma or a supernumerary tooth. Conclusion: In our study, the prevalence of agenesis of the lateral incisors was higher in Japanese children than in other populations, and eruption disturbance occurred less frequently than agenesis and microdontia. Nevertheless, the early differential diagnosis of an eruption disturbance is important in order to begin appropriate treatment at the optimal time.

Lethal Hypoplasia and Developmental Anomalies of the Lungs in a Newborn with Intrauterine Adrenal Hemorrhage and Cerebral Infarcts: A Proposed Pulmonary Disruption Sequence

2014 ◽  
Vol 17 (5) ◽  
pp. 374-381 ◽  
Author(s):  
Terakeith Lertsburapa ◽  
Diana Vargas ◽  
Geralyn Lambert-Messerlian ◽  
Umadevi Tantravahi ◽  
Füsun Gündoğan ◽  
...  
Keyword(s):  
Adrenal Hemorrhage ◽  
Cerebral Infarcts ◽  
Developmental Anomalies

Construction of chimeric thymuses in the mouse fetus byin utero surgery

1986 ◽  
Vol 16 (5) ◽  
pp. 523-530 ◽  
Author(s):  
Josselyne Salaün ◽  
Françoise Calman ◽  
Monique Coltey ◽  
Nicole M. Le Douarin
Keyword(s):  
Mouse Fetus

TET2‐Mediated Spatiotemporal Changes of 5‐Hydroxymethylcytosine During Organogenesis in the Late Mouse Fetus

2018 ◽  
Vol 302 (6) ◽  
pp. 954-963 ◽  
Author(s):  
Xiangjun Li ◽  
Fangfang Xie ◽  
Junfeng Jin ◽  
Yuqiong Wu ◽  
Ziwei Luo ◽  
...  
Keyword(s):  
Mouse Fetus ◽  
Spatiotemporal Changes
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