Stable overexpression of mutated PTEN in Chinese hamster ovary cells enhances their performance and therapeutic antibody production

2021 ◽  
pp. 2000623
Author(s):  
Qin Zhou ◽  
Yujie Zhang ◽  
Xiaoxiang Lu ◽  
Chang Wang ◽  
Xinxin Pei ◽  
...  
Keyword(s):  
Antibody Production ◽  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Therapeutic Antibody ◽  
Ovary Cells ◽  
Therapeutic Antibody Production

Inactivation of deubiquitinase CYLD enhances therapeutic antibody production in Chinese hamster ovary cells

2018 ◽  
Vol 102 (14) ◽  
pp. 6081-6093 ◽  
Author(s):  
Yafang Lu ◽  
Qin Zhou ◽  
Qianqian Han ◽  
Pengfei Wu ◽  
Lanlan Zhang ◽  
...  
Keyword(s):  
Antibody Production ◽  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Therapeutic Antibody ◽  
Ovary Cells ◽  
Therapeutic Antibody Production

scholarly journals A comparative analysis of recombinant Fab and full‐length antibody production in Chinese hamster ovary cells

2021 ◽  
Author(s):  
Hirra Hussain ◽  
Tulshi Patel ◽  
Angelica M. S. Ozanne ◽  
Davide Vito ◽  
Mark Ellis ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Antibody Production ◽  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Full Length ◽  
Ovary Cells

Effect of the disulfide isomerase PDIa4 on the antibody production of Chinese hamster ovary cells

2020 ◽  
Vol 130 (6) ◽  
pp. 637-643
Author(s):  
Kei Komatsu ◽  
Kento Kumon ◽  
Mayuno Arita ◽  
Masayoshi Onitsuka ◽  
Takeshi Omasa ◽  
...  
Keyword(s):  
Antibody Production ◽  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Ovary Cells ◽  
Disulfide Isomerase

scholarly journals Very high density of Chinese hamster ovary cells in perfusion by alternating tangential flow or tangential flow filtration in WAVE bioreactor™—part II: Applications for antibody production and cryopreservation

2013 ◽  
Vol 29 (3) ◽  
pp. 768-777 ◽  
Author(s):  
Marie‐Françoise Clincke ◽  
Carin Mölleryd ◽  
Puneeth K Samani ◽  
Eva Lindskog ◽  
Eric Fäldt ◽  
...  
Keyword(s):  
Antibody Production ◽  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
High Density ◽  
Ovary Cells ◽  
Tangential Flow ◽  
Wave Bioreactor ◽  
Flow Filtration ◽  
Very High

Optimization of chemically defined feed media for monoclonal antibody production in Chinese hamster ovary cells

2015 ◽  
Vol 120 (1) ◽  
pp. 78-84 ◽  
Author(s):  
Shohei Kishishita ◽  
Satoshi Katayama ◽  
Kunihiko Kodaira ◽  
Yoshinori Takagi ◽  
Hiroki Matsuda ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Antibody Production ◽  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Monoclonal Antibody Production ◽  
Ovary Cells

Heuristic Optimization of Antibody Production by Chinese Hamster Ovary Cells

2005 ◽  
Vol 21 (5) ◽  
pp. 1537-1542 ◽  
Author(s):  
S. Sandadi ◽  
S. Ensari ◽  
B. Kearns
Keyword(s):  
Antibody Production ◽  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Heuristic Optimization ◽  
Ovary Cells

scholarly journals Nutrient supplementation strategy improves cell concentration and longevity, monoclonal antibody production and lactate metabolism of Chinese hamster ovary cells

Bioengineered ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 463-471 ◽  
Author(s):  
Saumel Pérez-Rodriguez ◽  
María de Jesús Ramírez-Lira ◽  
Mauricio A. Trujillo-Roldán ◽  
Norma A. Valdez-Cruz
Keyword(s):  
Monoclonal Antibody ◽  
Antibody Production ◽  
Chinese Hamster Ovary ◽  
Cell Concentration ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Lactate Metabolism ◽  
Monoclonal Antibody Production ◽  
Nutrient Supplementation ◽  
Ovary Cells
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