Overview of the 2006 Food and Drug Administration Circulatory System Devices Panel meeting on drug-eluting stent thrombosis

2007 ◽  
Vol 69 (7) ◽  
pp. 1064-1074 ◽  
Author(s):  
Tina L. Pinto Slottow ◽  
Ron Waksman
Keyword(s):  
Stent Thrombosis ◽  
Drug Administration ◽  
Food And Drug Administration ◽  
Circulatory System ◽  
Drug Eluting Stent ◽  
Drug Eluting

scholarly journals Late thrombosis of coronary bare-metal stent: Case report

2006 ◽  
Vol 134 (3-4) ◽  
pp. 155-158 ◽  
Author(s):  
Svetlana Apostolovic ◽  
Zoran Perisic ◽  
Miloje Tomasevic ◽  
Goran Stankovic ◽  
Milan Pavlovic ◽  
...  
Keyword(s):  
Stent Thrombosis ◽  
Bare Metal Stent ◽  
Drug Eluting Stent ◽  
Bare Metal ◽  
Metal Stent ◽  
Coronary Syndrome ◽  
Percutaneous Coronary ◽  
Drug Eluting ◽  
Late Thrombosis ◽  
And Control

Stent thrombosis remains the primary cause of death after percutaneous coronary interventions (PCI). Despite modern concepts of PCI, stent thrombosis occurs in 0.5% -2% of elective procedures and even 6% of patients with the acute coronary syndrome (ACS). Stent thrombosis most often develops within the first 48 hours after the PCI, and rarely after a week of stent implantation. Angiographically documented late (>6 months) thrombosis of coronary bare-metal stent (BMS) is rare, because the stent endothelialization is considered to be completed after four weeks of the intervention. Our patient is a 41 year old male and he had BMS thrombosis 345 days after the implantation, which was clinically manifested as an acute myocardial infarction in the inferoposterolateral localization. Stent Clinical Centre of Serbia, Belgrade thrombosis occurred despite a long term dual antiplatelet therapy and control of known risk factors. Thrombolytic therapy (Streptokinase in a dose of 1 500 000 IU) was not successful in reopening the occluded vessel, so the flow through the coronary artery was achieved by rescue balloon angioplasty, followed by implantation of drug eluting stent in order to prevent restenosis.

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