Computational Mutation Analysis of Hydrogen Abstraction and Radical Rearrangement Steps in the Catalysis of Coenzyme B12-Dependent Diol Dehydratase

2007 ◽  
Vol 13 (28) ◽  
pp. 7864-7873 ◽  
Author(s):  
Takashi Kamachi ◽  
Tetsuo Toraya ◽  
Kazunari Yoshizawa
Keyword(s):  
Mutation Analysis ◽  
Hydrogen Abstraction ◽  
Coenzyme B12 ◽  
Diol Dehydratase ◽  
Radical Rearrangement

What is the Identity of the Metal Ions in the Active Sites of Coenzyme B12-Dependent Diol Dehydratase? A Computational Mutation Analysis

2009 ◽  
Vol 113 (25) ◽  
pp. 8435-8438 ◽  
Author(s):  
Takashi Kamachi ◽  
Masanori Takahata ◽  
Tetsuo Toraya ◽  
Kazunari Yoshizawa
Keyword(s):  
Metal Ions ◽  
Mutation Analysis ◽  
Active Sites ◽  
Coenzyme B12 ◽  
Diol Dehydratase

Mechanism-based Inactivation of Coenzyme B12-dependent Diol Dehydratase by 3-Unsaturated 1,2-Diols and Thioglycerol

2008 ◽  
Vol 144 (4) ◽  
pp. 437-446 ◽  
Author(s):  
T. Toraya ◽  
N. Tamura ◽  
T. Watanabe ◽  
M. Yamanishi ◽  
N. Hieda ◽  
...  
Keyword(s):  
Coenzyme B12 ◽  
Diol Dehydratase

scholarly journals Structural Rationalization for the Lack of Stereospecificity in Coenzyme B12-dependent Diol Dehydratase

2003 ◽  
Vol 278 (25) ◽  
pp. 22717-22725 ◽  
Author(s):  
Naoki Shibata ◽  
Yuka Nakanishi ◽  
Masaki Fukuoka ◽  
Mamoru Yamanishi ◽  
Noritake Yasuoka ◽  
...  
Keyword(s):  
Coenzyme B12 ◽  
Diol Dehydratase

Functions of the D-Ribosyl Moiety and the Lower Axial Ligand of the Nucleotide Loop of Coenzyme B12 in Diol Dehydratase and Ethanolamine Ammonia-lyase Reactions

2002 ◽  
Vol 132 (6) ◽  
pp. 935-943 ◽  
Author(s):  
M. Fukuoka ◽  
S. Yamada ◽  
S. Miyoshi ◽  
K. Yamashita ◽  
M. Yamanishi ◽  
...  
Keyword(s):  
Axial Ligand ◽  
Coenzyme B12 ◽  
Diol Dehydratase
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