scholarly journals Mechanism of Oxidative Activation of Fluorinated Aromatic Compounds by N‐Bridged Diiron‐Phthalocyanine: What Determines the Reactivity?

2019 ◽  
Vol 25 (63) ◽  
pp. 14320-14331 ◽  
Author(s):  
Cédric Colomban ◽  
Anthonio H. Tobing ◽  
Gourab Mukherjee ◽  
Chivukula V. Sastri ◽  
Alexander B. Sorokin ◽  
...  
Keyword(s):  
Aromatic Compounds ◽  
Oxidative Activation ◽  
Fluorinated Aromatic Compounds

scholarly journals Cover Feature: Mechanism of Oxidative Activation of Fluorinated Aromatic Compounds by N‐Bridged Diiron‐Phthalocyanine: What Determines the Reactivity? (Chem. Eur. J. 63/2019)

2019 ◽  
Vol 25 (63) ◽  
pp. 14255-14255
Author(s):  
Cédric Colomban ◽  
Anthonio H. Tobing ◽  
Gourab Mukherjee ◽  
Chivukula V. Sastri ◽  
Alexander B. Sorokin ◽  
...  
Keyword(s):  
Aromatic Compounds ◽  
Oxidative Activation ◽  
Fluorinated Aromatic Compounds

ChemInform Abstract: METAL-AMMONIA REDUCTION OF FLUORINATED AROMATIC COMPOUNDS

1977 ◽  
Vol 8 (48) ◽  
pp. no-no
Author(s):  
D. W. JESSUP ◽  
J. W. PASCHAL ◽  
P. W. RABIDEAU
Keyword(s):  
Aromatic Compounds ◽  
Fluorinated Aromatic Compounds

Synthesis of Fluorinated Aromatic Compounds by One-Pot Benzyne Generation and Nucleophilic Fluorination

2014 ◽  
Vol 67 (3) ◽  
pp. 475 ◽  
Author(s):  
Takashi Ikawa ◽  
Shigeaki Masuda ◽  
Tsuyoshi Nishiyama ◽  
Akira Takagi ◽  
Shuji Akai
Keyword(s):  
Aromatic Compounds ◽  
Biologically Active ◽  
Reaction Conditions ◽  
Fluoride Ions ◽  
One Pot ◽  
Substituted Benzenes ◽  
Fluorinated Aromatic Compounds ◽  
Nucleophilic Fluorination ◽  
Sequential Reactions

The fluorination of substituted benzenes using fluoride ions under mild reaction conditions has been one of the most important challenges for the synthesis of biologically active fluorinated aromatic compounds; however, only a few synthetically useful methods are known. In this paper, it is reported that the nucleophilic fluorination of benzynes, generated from either 2-(trialkylsilyl)phenyl nonafluorobutanesulfonates or 2-(trialkylsilyl)phenols, meets this challenge. In particular, the fluorination starting from 2-(trialkylsilyl)phenols for fabricating aryl fluorides involves three sequential reactions in one-pot: the nonaflylation of phenols, benzyne generation, and nucleophilic fluorination of the benzynes. The regioselectivities of these reactions are controlled by the substituents at the C3-position of the benzynes.

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