ChemInform Abstract: CARBOXYLIC ACID-DICHLOROPHOSPHORIC ACID ANHYDRIDES - REACTIVE INTERMEDIATES IN ACID CHLORIDE PREPARATION WITH PHOSPHORYL CHLORIDE

1978 ◽  
Vol 9 (49) ◽  
Author(s):  
F. EFFENBERGER ◽  
G. KOENIG ◽  
H. KLENK
Keyword(s):  
Carboxylic Acid ◽  
Acid Chloride ◽  
Reactive Intermediates ◽  
Phosphoryl Chloride ◽  
Acid Anhydrides

scholarly journals Harnessing Chemical Energy for the Activation and Joining of Prebiotic Building Blocks

2019 ◽  
Author(s):  
Ziwei Liu ◽  
Long-Fei Wu ◽  
Jianfeng Xu ◽  
Claudia Bonfio ◽  
David Russell ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Carboxylic Acid ◽  
Peptide Nucleic Acid ◽  
Reactive Intermediates ◽  
Building Blocks ◽  
Acid System ◽  
Rna Oligomers ◽  
Prebiotic Activation ◽  
Simultaneous Activation ◽  
Acid Anhydrides

Simultaneous activation of carboxylates and phosphates provides multiple pathways for the generation of reactive intermediates, including mixed carboxylic acid-phosphoric acid anhydrides, for the synthesis of peptidyl-RNAs, peptides, RNA oligomers and primordial phospholipids. These results indicate that unified prebiotic activation chemistry could have enabled the joining of building blocks in aqueous solution from a common pool and enabled the progression of a system towards higher complexity foreshadowing the modern encapsulated peptide-nucleic acid system

scholarly journals Harnessing Chemical Energy for the Activation and Joining of Prebiotic Building Blocks

2019 ◽  
Author(s):  
Ziwei Liu ◽  
Long-Fei Wu ◽  
Jianfeng Xu ◽  
Claudia Bonfio ◽  
David Russell ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Nucleic Acid ◽  
Carboxylic Acid ◽  
Peptide Nucleic Acid ◽  
Reactive Intermediates ◽  
Building Blocks ◽  
Rna Oligomers ◽  
Prebiotic Activation ◽  
Simultaneous Activation ◽  
Acid Anhydrides

Simultaneous activation of carboxylates and phosphates provides multiple pathways for the generation of reactive intermediates, including mixed carboxylic acid-phosphoric acid anhydrides, for the synthesis of peptidyl-RNAs, peptides, RNA oligomers and primordial phospholipids. These results indicate that unified prebiotic activation chemistry could have enabled the joining of building blocks in aqueous solution from a common pool and enabled the progression of a system towards higher complexity foreshadowing the modern encapsulated peptide-nucleic acid systemThis paper has been accepted by Nature Chemistry<div>https://www.nature.com/articles/s41557-020-00564-3<br></div>

ChemInform Abstract: Acylation of Hydroxyethyl Hydrazine by Carboxylic Acid Anhydrides.

1986 ◽  
Vol 17 (36) ◽  
Author(s):  
V. V. SHEVCHENKO ◽  
G. A. VASIL'EVSKAYA ◽  
N. S. KLIMENKO ◽  
S. N. LOSHKAREVA ◽  
T. S. KHRAMOVA
Keyword(s):  
Carboxylic Acid ◽  
Acid Anhydrides
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