ChemInform Abstract: STEREOCHEMICAL STUDIES. LVIII. SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS BY THE E NOVEL USE OF MESO-COMPOUND. 2. EFFICIENT SYNTHESIS OF AN OPTICALLY PURE STEROID INTERMEDIATE

1981 ◽  
Vol 12 (10) ◽  
Author(s):  
M. NARA ◽  
S. TERASHIMA ◽  
S. YAMADA
Keyword(s):  
Optically Active ◽  
Efficient Synthesis ◽  
Active Compounds ◽  
Optically Pure

scholarly journals Synthesis of 2-Amino-apopinan-3-ol and Applications of Its Derivatives in Asymmetric Reduction of Ketones

Proceedings ◽  
2019 ◽  
Vol 41 (1) ◽  
pp. 63
Author(s):  
Anna Kmieciak ◽  
Marek P. Krzemiński
Keyword(s):  
Amino Alcohol ◽  
Asymmetric Reduction ◽  
Optically Active ◽  
Asymmetric Reactions ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Active Compounds ◽  
Reduction Methods ◽  
Optically Pure ◽  
Reduction Of Ketones

Monoterpenes are optically active compounds which occur in nature. This fact makes them interesting precursors for the synthesis of optically active ligands, which can be applied in various asymmetric reactions. In this work, we present the synthesis of optically pure 2-amino-apopinan-3-ol from (−)-α-pinene. The obtained amino alcohol was used as a precursor of oxazaborolidine, which was used as catalyst in the asymmetric reduction of aryl-alkyl ketones with borane. In the second part, we transformed 2-amino-apopinan-3-ol into PHOX ligand in a three-step reaction. The complex of ruthenium precursor with PHOX ligand was used as a catalyst in the asymmetric transfer hydrogenation of aryl-alkyl ketones. Alcohols with enantiomeric excesses of up to 97% were isolated using both reduction methods.

scholarly journals A one-step, modular route to optically-active diphos ligands

2015 ◽  
Vol 51 (50) ◽  
pp. 10206-10209 ◽  
Author(s):  
E. Louise Hazeland ◽  
Andy M. Chapman ◽  
Paul G. Pringle ◽  
Hazel A. Sparkes
Keyword(s):  
Optically Active ◽  
Elimination Reaction ◽  
Efficient Synthesis ◽  
One Step ◽  
Optically Pure

A chlorosilane elimination reaction has been developed that allows the efficient synthesis of optically pure C1-symmetric, C1-backboned diphosphines with a wide variety of stereoelectronic characteristics.

A highly efficient synthesis of optically pure γ-iodo allylic alcohols and their conversion into various optically active allylic alcohols

1987 ◽  
Vol 28 (50) ◽  
pp. 6351-6354 ◽  
Author(s):  
Yasunori Kitano ◽  
Takashi Matsumoto ◽  
Takenori Wakasa ◽  
Sentaro Okamoto ◽  
Toshiyuki Shimazaki ◽  
...  
Keyword(s):  
Optically Active ◽  
Allylic Alcohols ◽  
Efficient Synthesis ◽  
Highly Efficient ◽  
Optically Pure

Rapid and Efficient Synthesis of Optically Active Pyrazoles under Solvent-Free Conditions.

ChemInform ◽  
2005 ◽  
Vol 36 (8) ◽  
Author(s):  
J. S. Yadav ◽  
B. V. S. Reddy ◽  
G. Satheesh ◽  
P. Naga Lakshmi ◽  
S. Kiran Kumar ◽  
...  
Keyword(s):  
Optically Active ◽  
Solvent Free ◽  
Efficient Synthesis ◽  
Solvent Free Conditions
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