ChemInform Abstract: Total Synthesis of (-)-Oudemansin X (IX) Based on Enzymatic Resolution Using Immobilized Lipase.

ChemInform ◽  
2010 ◽  
Vol 24 (40) ◽  
pp. no-no
Author(s):  
H. AKITA ◽  
I. UMEZAWA ◽  
M. NOZAWA ◽  
S. NAGUMO
Keyword(s):  
Total Synthesis ◽  
Immobilized Lipase ◽  
Enzymatic Resolution

Total synthesis of (−)-oudemansin X based on enzymatic resolution using immobilized lipase

1993 ◽  
Vol 4 (5) ◽  
pp. 757-760 ◽  
Author(s):  
Hiroyuki Akita ◽  
Isao Umezawa ◽  
Masako Nozawa ◽  
Shinji Nagumo
Keyword(s):  
Total Synthesis ◽  
Immobilized Lipase ◽  
Enzymatic Resolution

scholarly journals Diastereoselective Total Synthesis of (+)-Raputindole A: An Iridium- Catalyzed Cyclization Approach

2020 ◽  
Author(s):  
Ronaldo Pilli ◽  
Juliana Lira Luna Freire Regueira ◽  
Luiz Fernando Silva Jr.
Keyword(s):  
Total Synthesis ◽  
Heck Reaction ◽  
Enzymatic Resolution ◽  
Enantiomerically Pure ◽  
Tricyclic Core ◽  
Benzylic Alcohol ◽  
Convergent Approach

This work describes the total synthesis of Raputindole A <b>(1)</b> through a convergent approach which features: 1) an iridium-catalyzed cyclization to assembly the tricyclic core of the northern part, 2) enzymatic resolution to secure the preparation of enantiomerically pure benzylic alcohol, 3) installation of the butenyl substituent via methallylation of the corresponding benzylic carbocation and coupling of the northern and southern parts via Heck reaction. (+)-Raputindole A <b>(1)</b> was prepared in 10 steps (LLS) and 10% overall yield.

ChemInform Abstract: Enzymatic Resolution of Indene Bromohydrin Acetate Using Immobilized Lipase.

ChemInform ◽  
2010 ◽  
Vol 29 (6) ◽  
pp. no-no
Author(s):  
Y. IGARASHI ◽  
S. OTSUTOMO ◽  
M. HARADA ◽  
S. NAKANO
Keyword(s):  
Immobilized Lipase ◽  
Enzymatic Resolution

Total synthesis of (−)-(8R, 10S)- and (+)-(8S, 10R)-8-hydroxypolypoda-13,17,21-triene based on enzymatic resolution

2003 ◽  
Vol 22 (3-4) ◽  
pp. 161-172 ◽  
Author(s):  
Masako Kinoshita ◽  
Daisuke Nakamura ◽  
Naoko Fujiwara ◽  
Hiroyuki Akita
Keyword(s):  
Total Synthesis ◽  
Enzymatic Resolution

Total synthesis of 12-O-benzoyl-6,7,14,15-tetradehydro leukotriene B4 methyl ester: precursor of labeled LTB4

1989 ◽  
Vol 67 (12) ◽  
pp. 2240-2242 ◽  
Author(s):  
Renée Pontikis ◽  
Lalatiana R. Randrianasolo ◽  
Yves Le Merrer ◽  
Nguyen Hoang Nam ◽  
Robert Azerad ◽  
...  
Keyword(s):  
Methyl Ester ◽  
Total Synthesis ◽  
Leukotriene B4 ◽  
Enzymatic Resolution ◽  
Propargylic Alcohol

12-O-Benzoyl-6,7,14,15-tetradehydroleukotriene B4 methyl ester 1, the direct precursor of isotopically labeled LTB4's, has been prepared. This synthesis was accomplished by the assembly of two key chirons: α-hydroxyaldehyde of R configuration, 2, and propargylic alcohol of S configuration, (S)-7. The first was obtained from D-mannitol whereas the second was obtained by enzymatic resolution. Keywords: leukotriene B4, tetradehydroleukotriene B4, labeling, chiral α-hydroxyaldehyde, enzymatic resolution.

Enzymatic resolution of indene bromohydrin acetate using immobilized lipase

1997 ◽  
Vol 8 (16) ◽  
pp. 2833-2837 ◽  
Author(s):  
Yoshio Igarashi ◽  
Shinya Otsutomo ◽  
Masayuki Harada ◽  
Shigeru Nakano
Keyword(s):  
Immobilized Lipase ◽  
Enzymatic Resolution
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