ChemInform Abstract: Nucleosides and Nucleotides. Part 146. New Neplanocin Analogues. Part 5. A Potent Adenosylhomocysteine Hydrolase Inhibitor Lacking Antiviral Activity. Synthesis and Antiviral Activity of 6′-Carboxylic Acid Derivatives of Neplanocin A.

ChemInform ◽  
2010 ◽  
Vol 27 (43) ◽  
pp. no-no
Author(s):  
T. OBARA ◽  
S. SHUTO ◽  
Y. SAITO ◽  
M. TORIYA ◽  
K. OGAWA ◽  
...  
Molecules ◽  
2006 ◽  
Vol 11 (12) ◽  
pp. 968-977 ◽  
Author(s):  
Mario Sechi ◽  
Fabio Casu ◽  
Ilaria Campesi ◽  
Stefano Fiori ◽  
Alberto Mariani

ChemInform ◽  
2010 ◽  
Vol 28 (3) ◽  
pp. no-no
Author(s):  
T. OBARA ◽  
S. SHUTO ◽  
Y. SAITO ◽  
R. SNOECK ◽  
G. ANDREI ◽  
...  

2021 ◽  
Vol 11 (3) ◽  
pp. 1180
Author(s):  
Kinga Paruch ◽  
Łukasz Popiołek ◽  
Anna Biernasiuk ◽  
Anna Berecka-Rycerz ◽  
Anna Malm ◽  
...  

Bacterial infections, especially those caused by strains resistant to commonly used antibiotics and chemotherapeutics, are still a current threat to public health. Therefore, the search for new molecules with potential antimicrobial activity is an important research goal. In this article, we present the synthesis and evaluation of the in vitro antimicrobial activity of a series of 15 new derivatives of 4-methyl-1,2,3-thiadiazole-5-carboxylic acid. The potential antimicrobial effect of the new compounds was observed mainly against Gram-positive bacteria. Compound 15, with the 5-nitro-2-furoyl moiety, showed the highest bioactivity: minimum inhibitory concentration (MIC) = 1.95–15.62 µg/mL and minimum bactericidal concentration (MBC)/MIC = 1–4 µg/mL.


1983 ◽  
Vol 14 (13) ◽  
Author(s):  
Z. V. VLASOVA ◽  
R. S. BELEN'KAYA ◽  
A. E. LIPKIN ◽  
I. K. MOISEEV ◽  
M. M. TIMOFEEVA ◽  
...  

2008 ◽  
Vol 52 (1) ◽  
pp. 605-606 ◽  
Author(s):  
J. Fogt ◽  
P. Januszczyk ◽  
G. Framski ◽  
T. Onishi ◽  
K. Izawa ◽  
...  

1960 ◽  
Vol 2 (3) ◽  
pp. 263-269 ◽  
Author(s):  
Paolo Da Re ◽  
Lucia Verlicchi ◽  
Ivo Setnikar

2016 ◽  
Vol 349 (6) ◽  
pp. 442-455 ◽  
Author(s):  
Karanam Anandan Suresh ◽  
Venkata Subbaiah C. Kadiam ◽  
Thaslim S. K. Basha ◽  
Naga Raju Chamarti ◽  
Suresh M. Kumar ◽  
...  

Heterocycles ◽  
1997 ◽  
Vol 45 (4) ◽  
pp. 787 ◽  
Author(s):  
Yvette A. Jackson ◽  
Mark F. Williams

1984 ◽  
Vol 21 (3) ◽  
pp. 681-683 ◽  
Author(s):  
Raymond Houssin ◽  
Jean-Luc Bernier ◽  
Jean-Pierre Hénichart

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